Infectious Disease Flashcards

(50 cards)

1
Q

Three most common causes of PUO

A

Infection
Cancer
Autoimmune disease

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2
Q

Signs and symptoms of streptococcal pharyngitis

A

Fever, tender anterior cervical lymphadenopathy, tonsillar exudate, LACK of cough

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3
Q

Nonsuppurative complication of streptococcal infection that is not altered by treatment of primary infection

A

Post infectious glomerulonephritis

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4
Q

Most common predisposing factor for acute sinusitis

A

Viral URI

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5
Q

Asplenic patients are particularly susceptible to…

A

Encapsulated organisms:– pneumococcus, meningococcus, haemophilus influenzae, klebsiella

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6
Q

The number of bacteria needed on a clean-catch specimen to diagnose a UTI

A

10^5 bacteria/ml

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7
Q

Which healthy population in susceptible to UTIs?

A

Pregnant women –> Tx this group aggressively because of high risk of complications

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8
Q

A patient from California or Arizona presents with fever, malaise, cough, and night sweats.
Dx? Tx?

A

Coccidiodomycosis

Tx: amphotericin B

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9
Q

Non painful chancre

A

Primary syphilis

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10
Q

A ‘blueberry muffin’ rash is characteristic of what congenital infection?

A

Rubella

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11
Q

Meningitis in neonate
Causes?
Tx?

A

GBS, E.coli, Listeria

Tx: gentamicin & ampicillin

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12
Q

Meningitis in infants
Causes?
Tx?

A

Pneumococcus, meningococcus, H.influenzae

Tx: cefotaxime & vancomycin

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13
Q

What should always be done prior to LP?

A

Check for raised ICP

Look for papilloedema

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14
Q

CSF: low glucose, PMN predominance

A

Bacterial meningitis

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15
Q

CSF: normal glucose, lymphocytic predominance

A

Viral (aseptic) meningitis

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16
Q

CSF: numerous RBCs in serial CSF samples

A

Subarachnoid haemorrhage (SAH)

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17
Q

CSF: raised gamma globulins

A

Multiple sclerosis

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18
Q

Initially presents with a pruritic papule with regional lymphadenopathy; evolves into a black eschar after 7-10 days

Tx?

A

Cutaneous anthrax

Tx: penicillin G or ciprofloxacin

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19
Q

Findings in tertiary syphilis

A

Tabes dorsalis, general paresis, gummas, Argyll Robertson pupil, aortitis, aortic root aneurysms

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20
Q

Characteristics of secondary Lyme disease

A

Arthralgias, migratory polyarthropathies, Bell’s palsy, myocarditis

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21
Q

Cold agglutinins

22
Q

A 24 year old man presents with soft white plaques on his tongue and the back of his throat.
Dx? Work up? Tx?

A

Candidal thrush –> HIV test

Tx: nystatin oral suspension

23
Q

At what CD4 count should Pneumocystic jiroveci pneumonia prophylaxis be initiated in an HIV +ve?

Mycobacterium avium complex (MAC) prophylaxis?

A

<200 for P. Jiroveci (with TMP-SMX)
<50-100 for MAC

MAC prophylaxis: clarithromycin/erythromycin

24
Q

Rick factors for pyelonephritis

A
Pregnancy 
Vesicoureteric reflux 
Anatomical anomalies 
Indwelling catheters 
Kidney stones
25
Neutropenic nadir post- chemotherapy
7-10 days
26
Erythema migrans
Lesion for primary Lyme disease
27
Classic physical findings for endocarditis
Fever, new onset murmur, Oslers nodes, splinter haemorrhages, Janeway lesions, Roth spots
28
Aplastic crisis in sickle cell disease
Parvovirus B19
29
Branching rods in oral infection
Actinomyces israelii
30
Weakly gram positive, partially acid-fast in lung infection
Nocardia asteroides
31
Painful chancroid
Haemophilus ducreyi
32
Dog or cat bite
Pasteurella multocida
33
Gardener
Sporothrix schenckii
34
Raw pork and skeletal muscle cysts
Trichinella spiralis
35
Perianal itching
Enterobius vermicularis
36
Sheepherders with liver cysts
Echinococcus granulosus
37
Pregnant women with pets
Toxoplasma gondii
38
Meningitis in adults
Neisseria meningitidis
39
Meningitis in elderly
Streptococcus pneumoniae
40
Meningoenceohalitis in AIDS patients
Cryptococcus neoformans
41
Alcoholic with pneumonia
Klebsiella
42
"Currant jelly" sputum
Klebsiella
43
Malignant external otitis
Pseudomonas
44
Infection in burn victims
Pseudomonas
45
Osteomyelitis from a foot wound puncture
Pseudomonas
46
Osteomyelitis in a sickle cell patient
Salmonella
47
A 55 year old man who is a smoker and a heavy drinker presents with a new cough and flulike symptoms. Gram stain shows no organisms; silver stain sputum shows gram negative rods
Legionella pneumonia
48
A middle aged man presents with acute onset monoarticular joint pain and bilateral Bell palsy Dx? Transmission? Tx?
Lyme disease --> Ixodes tick Doxycycline
49
A patient develops endocarditis 3 weeks after receiving a prosthetic heart valve
Staph aureus OR staph epidermidis
50
A patient develops endocarditis in a native valve after having a dental cleaning
Streptococcus viridans