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Flashcards in Infectious Disease Deck (60):
1

symptoms of cervicitis

Vaginal dc (yellow, creamy, profuse)

2

how to dx gonorrhea

NAAT

3

MCC disseminated gonococcal cervicitis

acute septic arthritis, presents with joint pain

4

how to tx gonorrhea

ceftriaxone IM
cefixime PO + azithromycin PO

5

50% of people infected with gonorrhea are coinfected with

chlamydia

6

S/S chlamydia

clear/white discharge in men

7

common complication of chlamydia in men

reiters syndrome
-conjunctivitis
-urethritis
-arthritis

8

Fitz Hugh Curtis syndrome

-from GC or chlamydia
-liver adhesions form PID
-RUQ pain, LFTs normal

9

chlamydia tx

azithromycin PO

10

trichomonas tx

metronidazole
Clotrimazole vaginal suppositories for pregnant patients

11

where do scabies present

Lesions to finger webs, Flexor & extensor surfaces,

12

how to tx scabies

-permethrin 5%
-PO ivermectin

13

primary syphillus (treponema pallidium) presents with

-chancre (single painless ulcer at site of exposure, first manifestation)

14

secondary syphillus presents with

Maculopapular rash involving palms & soles week sot months after infection

15

tertiary syphillus presents with

neuro/cardio symptoms, ulcerating gumma months to year after secondary

16

how to dx syphillus

-RPR/VDRL are screening tests, - following tx
-FTA-ABS, MHA-TP are confirmatory, remains + after tx

17

how to tx primary adn secondary syphillus

-Benzathine PCN G
-tetra or doxy if allergic

18

HSV-1
HSV-2

-oral
-genital
multiple vesicles on an erythematous base, which eventually ulcerate

19

prodrome symptoms of herpes

tenderness, itching, burning or tingling prior to ulcer appearance

20

how to dx herpes

-Gold standard is Viral culture: Tzanck/Geimsa/ Wright smear multinucleated giant cells
-PCR is the most sensitive test available , but is limited by cost

21

how to tx first episode of herpes

-acyclovir PO TID
-famciclovir
-valacyclovir

22

how does herpes zoster present

Pain along course of a nerve followed by grouped vesicular lesions
Unilateral
same tx as herpes

23

HIV tests

-Enzyme immunoassay (EIA)= “screening test”
-Western blot (WB)= “confirmatory test”
-HIV viral load (measures copies/ mL)- often PCR

24

AIDS is defined as CD4 count <

200
PCP (MC opportunistic infection of AIDS, ground glass appearance on xray, tx with bactrim)
TB (upper lobe involvement)

25

advanced HIV w/CD4 count <50 can indicate

Mycobacterium avium complex (MAC)
Cytomegalovirus (CMV)

26

toxoplasma encephalitis presents with what on a CT

Ring-enhancing lesions w/ surrounding vasogenic edema

27

ophthalmic manifestations of AIDS

75% of pt’s w/ AIDS develop ocular complications
CMV retinitis - most frequent & serious ocular opportunistic infection & leading cause of blindness in AIDS patients
Herpes Zoster Ophthalmicus (dendritic lesions)-tx with IV acyclovir

28

how to tx CMV

ganciclovir or foscarnet

29

how to tx MAC

Clarithromycin + Ethambutol + Rifabutin

30

hwo to tx pulmonary TB

Isoniazid + Rifabutin + Pyrazinamide + Streptomycin

31

how to tx CNS toxoplasmosis

Pyrimethamine + Sulfadiazine + Folinic acid

32

how to tx CN cryptococcus

Amphotericin & Fluconazole

33

how to treat candidiasis

Clotrimazole or Nystatin

34

how to tx esophagitis

fluconazole

35

how to tx salmonellosis

cipro

36

cellulitis

Soft-tissue bacterial invasion m/c w/ Staphylococcus & Streptococcus in adults & Haemophilus influenzae in nonimmunized children

37

cellulitis presentation

Localized tenderness, warmth, erythema & induration
Progression to lymphangitis & lymphadenitis
Bacteremia w/ fever & chills

38

what labs should you order for suspected cellulits

Baseline labs + blood cultures + leukocyte counts+ lactic acid

39

hwo to tx outpt cellulitis
inpt

dicloxacillin, augmentin, clarithromycin
IV cefazolin or nafcillinm for DM ceftriaxone or imipenem

40

how to tx mild
moderate
severe MRSA

clinda or bactrim
clinda or vanco/linezolid if worsening
vanco or linezolid

41

Superficial cellulitis w/ lymphatic involvement: Group A Strep

erysipelas
Small area of erythema w/ burning sensation
Sharply demarcated erythema that is tense & painful
Lymphangitis & lymphadenitis commonly develops

42

how to tx erysipelas

PCN G

43

honey colored crusts

impetigo
tx w/mupirocin
if no response then PO anbx
Dicloxacillin
Cephalexin,
Amoxicillin-clavulanate

44

Recurrent infection of apocrine sweat glands (axilla & groin)

hiradenitis suppurativa

45

MCC foliculitis

p. aeruginosa

46

MCC furuncle/carbuncle

s. aureus

47

gas gangrene tx

Penicillin G + Vancomycin or penicillinase-resistant penicillin (nafcillin)
PCN allergic Clindamycin or metronidazole

48

rubella presents with

Maculopapular rash
Lymphadenopathy

49

rubeola (measles) presents with

Koplik spots, conjunctivitis
Red, blotchy (maculopapular) rash 3-7 days after prodromal symptoms appear

50

Roseola/Exanthem Subitum

-herpes virus
-transmitted via saliva

51

Pruritic rash consisting of crops of macules, papules, and vesicles (typically 250–500 lesions), presence of lesions in different stages of development at the same time

varicella

52

slapped cheek
B19 parvovirus

5th disease (erythema infectiosum)

53

, painful oral ulcers or blisters, body rash, followed by sores w/ blisters on palms & soles of feet

hanf, foot, mouth disease
coxsackie group A

54

Kawasackie disease

4/5 criteria must be met:
Conjunctivitis
Rash
Lymphadenopathy
Oropharyngeal changes (injection of pharynx & lips w/ prominent papillae of tongue (strawberry tongue)

55

how to tx Kawasackie

IV gamma globulin and ASA

56

“strawberry tongue” , sore throat, fever, ha, vomiting & abdominal pain

scarlet fever

57

how to tx scarlet fever

Abx (PCN) or erythromycin for PCN allergic (Abx shorten course &  incidence of rheumatic fever & nephritis)

58

complications of scarlet fever

Rheumatic fever, post streptococcal glomerulonephritis

59

how to tx rabies

HRIG (human rabies immune globulin) at wound site
Human diploid cell vaccine; administered Im/ intradermally on days 0,3,7, and 14

60

most virulent species of malaria

falciparium