Infectious Disease Flashcards
(267 cards)
1
Q
Drug of choice for Syphilis
A
Penicillin G
2
Q
When you see Gram(+) cocci in clusters, what do you cover for?
A
MRSA
3
Q
Treatment of choice for MRSA?
A
Vancomycin
4
Q
Best antibiotic for Methicillin-Sensitive Staph Aureus?
A
Cefazoline
5
Q
What bacteria to consider when seeing Gram(+) cocci in pairs and chains?
A
Streptococcus
6
Q
Gram(+) bacilli seen in gastroenteritis and meningitis?
A
Listeria
7
Q
Tx of choice for Bacillus anthracis?
A
Ciprofloxacin
8
Q
Tx of choice for Actinomyces?
A
Penicillin
9
Q
What organisms do Cephalosporin NOT cover?
A
LAME
- Listeria
- Atypicals
- MRSA (except Cefazoline)
- Enterococcus
10
Q
What is Catalase positive, Coagulase positive cocci?
A
Staph Aureus
11
Q
What are alpha-hemolytic Streptococcus?
A
Strep pneumo and Viridans
12
Q
What are beta-hemolytic Streptococcus?
A
S. pyogenes and S. agalactiae
13
Q
What are gamma-hemolytic streptococcus?
A
Enterococcus
14
Q
What type of cocci is Enterococcus?
A
Gram positive in pairs and chains.
15
Q
Enterococcus is not covered by ________.
A
Cephalosporins
16
Q
Best Tx for group A strep
A
Penicillin
17
Q
What anaerobes are resistant to penicillin?
A
Bacteroides spp.
18
Q
How does actinomyces present?
A
Abscess in the mandible, oral lesions
19
Q
Tx of choice for Listeria?
A
Ampicillin
20
Q
What do you need to treat Staph aureus?
A
Beta lactamase inhibitors + Penicillins
21
Q
When covering for cellulitis, you cover for what organisms?
A
Group A strep (pyogenes) and MSSA
22
Q
Tx of choice for cellulitis
A
1st gen cephalosporins
23
Q
Examples of 2nd gen cephalosporins
A
Cefoxitin and Cefotetan
24
Q
The only cephalosporins that treat for anaerobes?
A
2nd generation cephalosporins:
Cephamycins:
- Cefoxitin
- Cefotetan
25
Which cephalosporin is effective in covering MRSA?
Ceftaroline (5th gen)
26
Which cephalosporins treat PID?
2nd generations cephalosporins
27
What does clindamycin cover?
Strep, Staph, and Anaerobes
28
Best substitute for penicillin if patient has PCN allergy.
Clindamycin
29
Metronidazole is best for what organisms?
(GET the Metro)
Giardia
Entamoeba
Trichomonas
30
What is the best Tx for recurrent C. diff?
Fidaxomicin
31
Best diagnostic test for C. diff?
ELIZA test for C. diff toxin
32
How effective is fecal transplant?
95% effective
33
What is the best Tx for SEVERE C. diff?
Oral Vancomycin
34
How do you define SEVERE C. diff?
Any ONE of the following:
- WBC count over 15,000
- Increase of Creatinine of 1.5 or more
- over 60 y/o
- albumin less than 2.5
35
What drug, apart from an antibiotic, causes C. diff?
Proton pump inhibitors
36
What antibiotics increase risk of C. diff?
- Fluoroquinolones
- Broad spectrum cephalosporins
37
Safer antibiotics that have a low risk of C. diff occurrence
Tetracycline, Macrolides, and Bactrim
38
What antibiotics can you give to treat atypicals in pneumonia?
Macrolides
39
Cross reactivity for penicillin allergy and cephalosporins is \_\_\_\_%
less than 5%
40
What is your Vanco MIC (Minimum inhibitory concentration) cutoff to determine you cannot use Vancomycin?
Over 2.0
41
Substitutes for Vanco for MRSA?
- Daptomycin (Calcium paralyses cell)
SE: Myositis, neutralized by surfactants (cannot use for pneumonia)
For: cellulitis, right-sided endocarditis, skin infections, bacteremia
- Linezolid (inhibit cell wall synthesis)
SE: cannot use with SSRI, serotonin syndrome risk
For: good for pneumonia
42
Difference between serotonin syndrome and NMS
Myoclonus and hyperreflexia in serotonin syndrome.
No myoclonus and HYPOreflexia in NMS.
43
Most common side effect of Vanco
Thrombocytopenia
44
Ceftaroline is used for:
Pneumonia and Cellulitis
45
Macrolides are used for:
MILD gram positive infections
GOOD for atypical infections
BAD for serious gram pos infections
46
What organism must you cover with neutropenic fever?
Pseudomonas
47
If person has infected chemotherapy line what antibiotic do you give?
Vancomycin
48
What antibiotics can cover pseudomonas?
- Ceftazidime (3rd gen)
- Cefepime (4th gen)
- Pip/Taz
- Ticarcillin/Sulbactam (Beta lactams)
- Fluoroquinolones (ciprofloxacin is the best)
- Aminoglycosides
- Carbapenems (if with PCN allergy)
- Aztreonam (if with PCN allergy)
49
What conditions should you be wary of Pseudomonas?
CF, bronchiectasis
diabetics with malignant otitis externa
hot tub folliculitis
puncture wounds (with a nail)
nosocomial infections
50
Most common side effects of fluoroquinolones:
- tendinitis / tendon rupture
- peripheral neuropathy
- QT prolongation
- C. diff
51
Ceftazidime (3rd gen) covers
gram negative but not gram positive (strep/staph)
but good for pseudomonas
52
Cefepime (4th gen) can cover:
gram pos and gram neg
pseudomonas
53
Ceftriaxone (3rd gen) covers:
Broad spectrum for gram neg (Neisseria, etc)
can also cover pneumococcus
not good for pseudomonas
54
Why must you be careful with aminoglycosides?
It is nephrotoxic and ototoxic
55
What antibiotics have good anaerobic coverage?
Metronidazole
Moxifloxacin
Carbapenems
Beta-lactamases (ampi/sulba)
56
Which carbapenem does not cover pseudomonas?
Ertapenem
57
Carbapenems cover mostly gram negs, pseudomonas (except ertapenem), and anaerobes except:
MRSA
Enterococcus faecium
Stenotrophomonas maltophila (can be covered by bactrim)
58
What do we use to treat extended spectrum beta lactamases (ESBLs),
highly resistant gram negs.
Examples: E. coli, Klebsiella
Carbapenems (ertapenem)
Tigecycline
59
We can treat carbapenemase Klebsiella with:
Tigecycline or
Ceftazidime/avibactam (new beta lactamase inhibitor)
These mostly used for complicated UTIs and intrabdominal
60
How to treat multi drug resistant (MDR) pseudomonas?
Ceftolozane/Tazobactam
61
Where is doxycycline used?
Early lyme disease
Rickettsia
Chlamydia
Ehrlichiosis
62
What are the side effects of doxycycline?
Photosensitivity, pill esophagitis (drink lots of water)
63
Bactrim mostly used for:
PCP
Uncomplicated cystitis
64
Side effects of bactrim:
rash
SJS
thrombocytopenia, anemia, pancytopenia
kernicterus
hyperkalemia
decreased creatinine clearance
65
Do not give Bactrim with:
Ace-inhibitor
ARB
spironolactone
(Inhibit RAAS) - you can get arrhythmias due to hyperkalemia
66
Age cut off for covering listeria in patient's with meningitis?
Over 50 years old
| (Give ampicillin for listeria)
67
Why give vancomycin in patient's with meningitis?
20% of strep is penicillin resistant
68
What type of meningitis patients can get it from listeria?
HIV, steroids, lymphoma, leukemia, chemoTx, neonates and people over 50
69
How do you dx cryptococcal meningitis?
cryptococcal antigen
70
In patient's with HIV and cryptococcal meningitis, what is Tx algorithm?
Treat with HAART lifelong then star with induction phase of antigungals:
such as amphotericin and flucytosine then maintain with
fluconazole **until** CD4 count is **\>100 for 3 months**
71
Why give dexamethasone in strep meningitis?
Improves morbidity and mortality
72
Main causes of brain abscess in normal patient (non HIV): (organisms)
60-70% is Streptococcus
20-30% is Bacteroides
25-35% is Enterobacter
10% is Staphylococcus
73
Empiric Tx for brain abscess:
Penicillin (for the Strep, 60-70%) / or 3rd gen cephalosporin
Metronidazole (for the Bacteroides, 20-30%)
74
Main causes of brain abscess in HIV patients:
90% - Toxoplasmosis
75
How to Tx Toxo brain abscess in HIV patients
pyrimethamine and sulfadiazine for 10 days
76
If brain abscess comes from sinusitis infection, add ___ to treatment.
Add vancomycin (to cover MRSA)
77
With Herpes encephalitis, what happens if you have a negative PCR from your LP?
Repeat after 5 days, results may be negative in the early stages.
78
What indicates a West Nile encephalitis?
Happens in the summer
Lower extremity paralysis
79
First line Tx for otitis media?
Amoxicillin
then Augmentin or Macrolides
80
Sinusitis caused by:
90-98% caused by **VIRUSES**
81
When do you give antibiotics for sinusitis?
If symptoms persist for more than 10 days
if symptoms are severe (102 deg fever, facial pain for 3-4 consec days)
if symptoms worsen
82
Which organisms do you cover for sinusitis?
1. Strep pneumo
2. Haemophilus
3. Morzaxella
83
Antibiotics for sinusitis?
**Augmentin** (covers for s. pneumo and haemophilus, moraxella)
Doxycycline or New fluoroquinolone (if with PCN allergy)
84
What is the life-threatening side effect of augmentin?
Fulminant hepatotoxicity (antidote is NAC)
85
Which antibiotics can cause QT prolongation?
Macrolides and Fluoroquinolones
86
CENTAUR Criteria for pharyngitis
Cervical lymphadenopathy
Tonsillar Exudates
Fever
Lack of cough
87
When do you do a CT for meningitis?
FMD
seizures
papilledema
severe AMS
immunocompromised
88
When do you start empiric abx for meningitis?
IMMEDIATELY
89
When you see gram pos bacilli in CSF which sbx do you give?
Ampicillin (for listeria)
90
How to treat TB meningitis?
RIPE + steroids
91
How to treat TB pericarditis?
RIPE + steroids
92
Antibiotic Tx for Meningitis?
Ceftriaxone + Vancomycin
| (Strep pneumo + PCN resistant strep)
93
Tx for pharyngitis
Penicillin, ampicillin, amoxicillin
Macrolide, 1st gen ceph, clindamycin
94
CENTAUR for pharyngitis:
0-1 = ?
2-3 = ?
4 = ?
0-1 = do nothing
2-3 = rapid strep test
4 = treat
95
What drugs cover atypicals?
Fluoroquinolones
Macrolides
Doxycycline
96
What kind of rash do you see with coccidiomycoses?
Erythema nodosum
97
Tx for Chlamydia psittaci?
Doxycycline
98
Pneumonia with:
pancytopenia, hepatosplenomegaly, hilar lymphadenopathy, and NO RASH
Histoplasmosis
| (Histoplasma capsulatum)
99
Tx for CAP pneumonia?
New fluoroquinolones
(covers atypicals and PCN resistant pneumococcus)
100
Why not give macrolide only for pneumonia?
Does not cover PCN resistant pneumococcus
101
When can you give Macrolide monotherapy for pneumonia patients?
young, healthy, no comorbidities
102
If pneumonia patient has QT prolongation problems, and you can't give fluoroquinolones...
Give:
Ceftriaxone and Doxycycline
103
What are you covering in ventilator-assisted pneumonia?
Pseudomonas and MRSA
104
What pneumococcal vaccine do you give with patients \>65 y/o or immunocompromised?
Give covalent 13 then PPSV 23 a year later
105
Pneumococcal vaccine in lung, cardiac, liver, alcohol, smokers, **diabetics** but \<65?
PPSV 23
106
Pneumococcal vaccine in HIV, renal disease, hematological malignancies, transplant recipient, immunosuppressants, \<65 y/o
Covalent 13 now, then PPSV 23, 8 weeks later
107
108
Positive PPD and negative CXR, what do you give?
INH for 9 months
109
When do you perform inteferon gamma releasing assay for Tb dx?
When the patient has had BCG vaccine.
110
When do you NOT perform IFN-Y releasing assay?
In patient's with HIV and CD4 count \<200
111
PPD cutoff for high-risk patient (close contact)
\>5mm
112
PPD cutoff for medium risk (healthcare worker, homeless, etc)
\>10mm
113
PPD cutoff for low-risk patient
\>15mm
114
Multiple recurrent Giardia infection signifies...
Common Variable Immunodeficiency (Ig deficiency)
115
What is the most accurate diagnostic tool for Hepatocellular Ca?
Triple phase CT scan
116
Best screening tool for HCC?
Ultrasound
| (not AFP, only 80% reliable)
117
Patient with chronic liver disease must be screened for \_\_\_\_.
Hepatocellular Carcinoma
118
Treatment for Acute Hepatitis infection:
Supportive
119
Treatment for Chronic Hep B
Tenofovir, Entecavir
120
Common side effects of Tenofovir
Fanconi Syndrome and Osteoperosis
121
Who gets screened for Hep C?
IV drug users and people born from 1945 - 1965.
122
Most common treatment for Hep C?
For genotype 1 & 4:
Ledipasvir/Sofosbuvir regimen
Sofosbuvir/Velpatasvir regimen
For genotype 2 & 3:
Sofosbuvir and ribavirin
123
What is best dx test for gonorrhea?
Nucleic acid amplification test
124
Tx for gonorrhea:
IM ceftriaxone (PO no longer recommended)
125
Tx for chlamydia:
one dose of PO azithromycin or
7 days of doxycycline
126
When you diagnose gonorrhea, what do you treat for at the same time?
Chlamydia
127
When you diagnose chlamydia, do you treat for gonorrhea as well?
NO
128
Treatment for pelvic inflammatory disease (PID)?
Singe dose IM ceftriaxone and PO doxycycline for 2 weeks
129
130
What is screening for syphilis? Confirmatory?
Screening: VDRL, RPR
Confirmatory: FTA-ABS
131
Best study for Herpes?
PCR
or
Direct flourescent antibody test on scrapings (not serum)
132
If there is resistance to acyclovir et al, which do you use for herpes?
Foscarnet
133
What is this?
Erythema multiforme
134
Causes of this:
Most common: recurrent HSV
Sulfa drugs, phenytoin, NSAIDs
135
What is this? (tender to touch)
Erythema nodosum
136
When you see this with arthritis, plus b/l hilar lymphadenopathy,
what is the dx?
Sarcoidosis
137
When you see this plus diarrhea, what is the dx?
IBD
138
When you see this plus pneumonia, what is the dx?
Coccidiomycosis
139
3 choices for the treatment of uncomplicated cystitis:
Nitrofurantoin
Bactrim
Fosfomycin
(cipro no longer recommended for uncomplicated)
140
Tx for pyelonephritis:
Fluoroquinolone (except cipro - too broad)
Ampicillin
Gentamycin
3rd gen ceph. (ceftriaxone)
141
Diff. pyelonephritis from cystitis:
fever, cva tenderness
142
How many days of tx if complicated UTI?
14 days
143
What Tx for UTI with ESBL? (extended spectrum beta lactamases)
Carbapenems
144
First thing to check with male UTI?
Prostate
145
For UTI with prostatitis, what is Tx?
Same Abx treatment but 4 weeks long.
| (Fluoroqionolones with Bactrim)
146
What is best Tx for UTI in pregnancy?
Augmentin (Amox+Clav)
Cefixime
Cofpodoxime
(Nitro is 2nd line) - can cause kernicterus
147
Bactrim should not be used in pregnancy because of
kernicterus
148
Antibiotic of choice for recurrent UTI
daily or postcoital Bactrim
149
Why is nitro avoided in prostatitis?
Does not penetrate prostate
150
Only reason to use foley catheters.
urinary retention
151
What are you covering in PUSTULAR cellulitis?
MRSA
152
Out-patient options for MRSA treatment (PO)
Bactrim
Linazolid
Doxycycline
153
With diabetic ulcers/wounds, what organisms should you cover?
Pseudomonas, MRSA, and anaerobes
154
Most common organism involved in cellulitis?
MSSA and Group A strep (pyogenes)
155
Best Tx for non-pustular cellulitis:
Dicloxacillin or Cephalexin
156
How to differentiate Chronic Venous stasis from cellulitis?
Cellulitis is never bilateral.
157
Organisms in cat bites
Pasteurella
158
Organisms in human/dog bites
Eikenella, fusobacterium
159
Abx of choice for any bites:
**Best: Augmentin (Amox+Clav)**
Oral clindamycin plus fluoroquinolone (if with allergy)
Clinda + fluoroquinolone
Clinda + tetracycline
Clinda + Bactrim (for kids)
160
Best treatment for necrotizing fasciitis
**IMMEDIATE** surgical debridement
161
What is type 1 nec fasc?
Mixed flora
| (aerobes and anaerobes)
162
What is type 2 nec fasc?
One organism
| (usually Group A strep)
163
What is best treatment for infection of Group A strep?
Penicillin + Clindamycin
Clindamycin suppress toxin and kills non-replicating cells
164
Best treatment for this?
Penicillin with clindamycin
165
Treatment for Type 1 nec fasc
Vanco + clinda
and
pip/taz , cefepime/metro, or meropenem
(all this cover MRSA, pseudo, and anaerobes)
166
Tx for vibrio vulnificus?
3rd gen ceph (ceftriaxone)
and
Doxy or cipro
167
What is the best treatment for spontaneous bacterial peritonitis (SBP)?
Cefotaxime
or ceftriaxone
168
Best workup for osteomyelitis?
MRI
CT (if with hardware)
169
Do you treat osteomyelitis empirically?
No. Treat based on cultures of bone biopsy
170
What's the dx?
Osteomyelitis
171
Tx for this:
Antibiotics based on cultures
172
Dx for osteomyelitis?
MRI or CT or Xray then bone biopsy then culture/sensitivity
173
Do you culture the pus in osteomyelitis?
No
174
When can you treat OM (osteomyelitis) with oral meds?
When cultures are sensitive to cipro (fluoroquinolone) because they have good bioavailability
175
Most common cause of septic arthritis
Staph aureus
176
What makes an arthritis "septic"
White count \>50,000, low glucose
cultures positive in 90% of cases
177
When will septic arthritis have non-growing cultures?
Gonococcal arthritis
178
Patient has CHF due to aortic regurg brought about by bact. endocarditis. Replace valve? (Y/N)
Yes
179
Patient does not have CHF, but has aortic regurg brought about by bact. endocarditis. Replace valve? (Y/N)
No
180
Most common organism for bacterial endocarditis in addicts:
Strep viridans
181
Most common organism for bacterial endocarditis in prosthetic valve patients:
Staph epidermidis
182
Most common organism in native endocarditis?
Viridans strep
183
Tx for viridans endocarditis?
Penicillin for 4 weeks
or
Ceftriaxone + gentamycin for 2 weeks
or
Vanco if with PCN allergy
184
What is the empiric regimen for bacterial endocarditis with prosthetic valve:
Vancomycin, Gentamycin, **Rifampin**
185
Tx for endocarditis with MSSA:
Nafcillin + 5 days of gentamycin for 4-6 weeks
(gentamycin not used if with GFR \< 50)
or
Cefazoline (now best) + gentamycin
186
Tx for endocarditis with MRSA:
Vanco or dapto
| (no need for genta)
187
Tx for enterococcal endocarditis?
Penicillin or ampicillin
plus
gentamycin (continuously, not just for 5 days)
for 4-6 weeks
188
1st episode of septic emboli with endocarditis (without treatment), is this grounds for surgery valve replacement?
No.
It has to be recurrent septic emboli even with treatment.
189
Criteria for surgery of endocarditis:
* CHF
* recurrent emboli
* regurg that affect hemodynamics
* vegetation larger than 10 mm
* fungal growth
* recurrent bacterial infection/persistent bacteremia (\>5days)
* fistular abscess (heart block - PR prolongation is best sign for abscess)
190
When does a patient need prophylactic antibiotics with endocarditis?
* patients with prosthetic valves
* hx of IE
* most congenital malformations
* dental procedures with bleeding expected
*
191
Dx?
How do you know?
Pericarditis
Diffuse ST elevations
PR depression
192
What's on the arrow?
PR depression
| (seen in pericarditis)
193
Tx for pericarditis?
NSAIDs and colchicine
194
What is this?
Coxsackie B
195
What is this?
Chagas, Toxoplasmosis
196
What is this?
Non-specific ST-T wave change
197
What so you see in Echo in myocarditis?
left ventricular systolic dysfunction
198
Answer?
B. IV ceftriaxone
(Serious lyme disease - heart block, meningitis, etc)
199
Dx?
Lyme disease with HEART BLOCK
| (give ceftriaxone)
200
Migratory polyarthritis seen in...
Lyme disease
201
If you see this, what do you do? (next step)
Treat with doxycycline.
202
What is the Dx?
Babesiosis
203
Treatment for Babesiosis?
Oral atovaquone plus azithromycin for 7-10 days
204
Tx for SEVERE babesiosis?
Clindamycin + quinine
205
What is normal CD4 count?
700/mm3
206
What is the answer?
C. PO bactrim + prednisone + HAART
207
Diagnosis?
Pneumocystis pneumonia
208
How to know if PCP is severe?
Severe:
PaO2 of \<70 and
A-a gradient of \>35mmhg
209
Second-line options for PCP, if with sulfa allergy.
Primaquine + clindamycin
210
What abx to give for prophylaxis for PCP?
Dapsone
211
When do you give prophylaxis for PCP?
When CD count \<200
212
What's the answer?
D. Gancyclovir (has CMV)
213
Most common presentation of CMV?
Retinitis
214
When will HIV patient get CMV? What CD4 count?
\<50
215
HIV patient unable to swallow with CD4 count \<50. What is your Dx?
CMV
216
Patient got biopsy of the colon and saw this. What is your Dx?
(patient has HIV and CD4 count is 37)
CMV
217
Tx for CMV?
Valganciclovir
218
Tx for CMV retinitis?
Intravitreal ganciclovir
219
2nd line for ganciclovir (CMV tx)
Cidofovir or Foscarnet
220
Side effect of ganciclovir?
Neutropenia
221
Side effect of cidofovir or foscarnet?
Renal toxicity
222
What is the prophylactic antibiotic of choice for HIV patients with CD4 count of \<50?
Azithromycin 1200mg weekly
or
Clarithromycin 2x/day
(prophylaxis for MAC - mycobacterium avium complex)
223
Treatment for MAC in HIV patients:
clarithromycin and ethambutol +/- rifabutin
224
What is the answer?
C. Pyrimethamine and sulfadiazine
| (toxoplasmosis)
225
When does Toxo infect HIV patient? What CD4 count?
\<100
226
Where is CNS lymphoma most often seen?
Basal ganglia
227
What if patient has sulfa allergy and has toxo?
Replace sulfadiazine with clindamycin
228
What do you give to address bone marrow suppression of sulfadiazine?
Leucovorin
229
Fill blank
Answer
230
Prophylaxis for Toxo:
Bactrim
or
Dapsone with pyrimethamine
231
Patient with HIV and CD4 count 58. Dx?
Toxo
232
How to dx cryptococcal meningitis?
Cryptotoccal antigen in CSF via LP
233
What pneumococcal vaccines do you give HIV patients?
PS13 first then PPV23 8 weeks later
234
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235
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236
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237
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238
Answer?
C. HLA B5701
239
Answer?
240
What is the red blank?
241
What is the red blank?
242
What is the red blank?
243
What is the red blank?
244
Which ones do we use now?
245
What adverse effect does AZT have?
246
Fill blanks
247
Adverse effects of Tenofovir?
Fanconi syndrome, osteoporosis
248
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Inhibits P450 system (boosts effect)
249
Fill blanks
250
Most commonly used regimen for HIV therapy now:
2 nucleosides, 1 integrase inhibitor
251
Best combination now?
252
Which protease inhibitor (HIV drug) is a P450 inhibitor?
Ritonavir
253
Patient with Lyme disease given amox, but still has fevers. Why?
The patient also has anaplasma
254
Difference of Babesia from lyme?
Hemolytic anemia, jaundice, splenomegaly.
255
Anaplasma symptoms:
Leukpenia, thrombocytopenia, Î LFTs
256
Pre-exposure prophylaxis for HIV:
Tenofovir + Emtricitabine
257
Which HIV drug should not be given to pregnant women?
Efavirenz (teratogenic)
258
When do you start treating pregnant women with HIV to not pass it to the baby?
Right away
259
What do you give to a newborn born to a mother with HIV?
Give AZT during delivery and for 6 weeks after delivery.
260
When do you do C-section on pregnant woman with HIV?
IF viral load is \>1000
261
How to treat toxic shock syndrome?
Vancomycin and clindamycin
262
How to treat leptospirosis?
Penicillin, ceftriaxone OR doxycycline
263
Tx for plasm. falciparum malaria?
Mefloquine or atovaquone/proguanil
264
Tx for non-plasm. falciparum malaria?
Chloroquine or primaquine
265
Why not give quinine?
Cardiac arrhythmias
266
Tx for postherpetic neuralgia?
TCAs (desipramine), Anticonvulsants (gabapentin/pregabalin)
267
