infectious diseases

Question 1

what are SPICE organisms and name them

Answer 1

Organisms that very quickly develop resistance to beta-lactams/ 3rd gen. cephalosporins
S: Serratia spp.
P: Providencia
I: “indole-positive” Proteus spp. (this includes: P. vulgaris) *NOT P.mirabilis
C: Citrobacter spp.
E: Enterobacter spp.

Question 1

pathogens known to cause bloody diarrhea

Answer 1

Hemorrhagic E.Coli
Campylobacter
C.Diff
entamoeba
Shigella
Salmonella
Yersinia
Aeromonas

Question 2

Antibiotics safe in pregnancy

Answer 2

ceftriaxone
fosfomycin
beta lactamase, cephalosporins, aztreonam
Septra (+Folic acid in 1st trimester)
Isoniazid, Rifampicin, ethambutol

Question 3

Antibiotics contraindicated in pregnancy

Answer 3

Doxycycline

Question 4

Bacteremia of which species requires neoplasm work up

Answer 4

Streptococcus bovid
Streptococcus equinus
Require colonoscopy for neoplasm work up as per AHA and ID association of American and follow up colon in 4-6 months

Question 5

Risk factors for MRSA

Answer 5

High risk:
known MRSA colonized,
recurrent skin/soft tissue infxn,
Person who injects drugs,
central lines,
dialysis

Question 6

Risk factors for Multi drug resistant organisms

Answer 6

High risk:
previous abx within 3 months,
known MDR colonization,
local prevalence,
travel to endemic country or hospitalization abroad

Question 7

Patients at high risk for fungal infection

Answer 7

High risk:
neutropenia,
immunocompromised,
TPN,
dialysis,
chronic lines,
PWID, HIV, Heme or solid organ
transplant, emergency GI surgery or anastomotic leak