Infectious Diseases Flashcards

1
Q

What is menigitis?

A

An acute inflammation of the meningeal tissues of the brain and spinal cord.

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2
Q

What is the etiology of meningitis?

A

Infection (usually lungs or blood stream) or penetrating wounds

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3
Q

What are the major culprits of meningitis?

A

Streptococcus pneumoniae and neisseria meningitidis (bacteria)
Enteroviruses

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4
Q

Where does meningitis occur?

A

The pia mater, subarachnoid space, the ventricular system, and the CSF

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5
Q

When does meningitis occur?

A

Fall or winter

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6
Q

What does meningitis usually follow?

A

Infections like otitis or sinusitis, seen in immunocompromised states

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7
Q

How is meningitis spread?

A

Through respiratory droplets

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8
Q

Who is most at risk for meningitis?

A

Older adults, college students, and/or prisoners all due to close quarters

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9
Q

What is the patho behind meningitis?

A

Infection of arachnoid mater and CSF
Inflammatory response and pus secretion
Increase in CSF production
Increase in ICP

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10
Q

What is the classic triad with meningitis?

A

Fever, headache, and stiff neck

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11
Q

What are the clinical manifestations of meningitis?

A

N/V
Photophobia
Drowsiness can lead to coma
Seizures
Positive Kernig sign (resistance to leg extension)
Positive Brudzinski sign (neck flexion causes hip / knee flexion)

With meningococcus: skin rash, petechiae

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12
Q

What type of meningitis is the most common?

A

Acute bacterial

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13
Q

What is the fatality rate of acute bacterial meningitis?

A

Very high - can kill within hours
Need to start abx immediately

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14
Q

What are the long term effects of acute bacterial meningitis?

A

Hearing loss, seizures, and / or brain damage

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15
Q

What are the long term effects of acute viral meningitis?

A

Typically no long term effects

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16
Q

What are the most common medications for bacterial meningitis?

A

Ceftriaxzone and vancomycin (if the patient has MRSA form)

17
Q

What medication is used for patients with meningitis as a preventative for hepatic encephalitis?

A

Acyclovir

18
Q

What is encephalitis?

A

An acute inflammation of the brain.

19
Q

What is the etiology of encephalitis?

A

Viral
West nile encephalitis (mosquitos)
Measles, chicken pox, mumps
HSV1
Herpetic encephalitis

20
Q

What are the clinical manifestations of encephalitis?

A

Fever, headache, N/V, seizures

21
Q

How long for encephalitis manifestations to appear?

A

2-3 days after infection

22
Q

What is a brain abscess?

A

An accumulation of pus within the brain tissue

23
Q

What is the etiology of brain abscesses?

A

Commonly from an ear, tooth, mastoid, or sinus infection

24
Q

What are the clinical manifestations of brain abscesses?

A

Similar to meningitis / encephalitis - headache, fever, N/V
Increased IOP = drowsiness, confusion, seizures
May have focal symptoms based on where the abscess is