INFECTIOUS MONONUCLEOSIS Flashcards
0
Q
EBV is oncogenic for what?
A
Lymphoma
Nasopharyngeal cancer
Leiomyosarcoma
1
Q
How is it spread?
A
Sexual transmission
Salivary secretions
2
Q
Sx? And who do they normally hit?
A
Prodrome: fatigue, malaise headache
Sore throat
Fever
Fatigue
Systemic
- hepatitis
- glomerulonephritis
- pancreatitis
- pleural effusions
Neurological syndromes
- GBS
- meningoenxephalitis
- CN VII palsy
3
Q
What signs of EBV?
A
Low grade fever Lymphadenopathy Reddened pharynx Spleenomegaly Rash: macula papular, urticaria lot petechial
4
Q
Investigations?
A
CBE EUC LFT
Atypical lymphocytosis is key
- that is lymphocytes > 4500
- 10% atypical morphology
Paul BUNNEL test - EBV heterophile antibodies
If heterophile antibodies are negative, EBV specific antibodies IGM
5
Q
Rx of EBV?
A
Supportive
- paracetamol
- NSAIDs
- fluid good nutrition
- rest
If airway obstruction or life threatening, corticosteroids
6
Q
Complications of EBV?
A
Tonsillitis
SYSTEMIC EFFECTS
Splenic rupture is life threatening (hypovolemic shock)
HUS TTP
