inflammation Flashcards
(14 cards)
define inflammation
local change which occurs in living tissue when exposed to injury
which injury?
not severe enough to produce necrosis
causes of inflammation
physical
chemical
living agent
immunological disturbance
phenomena of acute inflammation
1_vascular change
2_margination an emigration of leucocytes
3_fromation of inflammatory extudate
vascular change
1momentary vasoconstriction
2 vasodilatation
3_inc the amount of blood flow (hyperaemia)
redness and hotness
emigration
vascular endothelial cells swollen
gaps are formed
PMNL and monocytes send pseudopodia and escape
subsequent mov of macrophage controlled by chemotaxis
marginaton
1_inc vascular permiability
2_extravasation of protein rich fluid
3_RBCs are conc
4inc viscosity and slow blood flow (stasis)
5 leucocytes leave axial stream
arrange them selves peripherally
what affect margination
adhesive molecules
what control mov
subsequent mov of macrophage controlled by chemotaxis
define exudate
mechanism
inc of filtiraton
inc hydrostatic
inc permiability of ptn
inc tissue osmotic pressure
composition
1_haematogenous part
2_histogenous (histiocytes _plasma cell_lymphcytes_mast)