Inflammation 2 Flashcards
(4 cards)
What is Rheumatic Fever (RF)
An acute, immunologically mediated multisystem inflammatory disease, caused by an abnormal host response to an infection with beta-hemolytic group A streptococci
Rheumatic fever (pathogenesis):
A hypersensitivity reaction induced by group A streptococci: antibodies directed against the bacterial M proteins, crossreact with normal proteins present in the heart, joints and other tissues
Hypersensitivity reactions def:
all forms of immune-mediated host tissue injury
READ:
- Hypersensitivity reactions - slide