INFLAMMATION Flashcards
(26 cards)
The enzyme that directly metabolize arachidonic acid?
Lipooxygenase
Intravascular force driving fluid out of the vasculature
Hydrostatic pressure
Excess fluid in body cavities?
Effusion
The enzyme target for non-steroid antiinflammatory drugs?
Cyclooxygenase
Activator of macrophages derived from the outer cell membrane of gram-negative bacteria
Lipopolysaccharide
Cell types that bind IgE molecules?
Mast cells and basophils
Edema fluid with low protein contents
Transudate
Activators of the alternative complement pathway?
Endotoxins
Complement components of the membrane attack complex (MAC)?
C5b-9
Not a phase of the acute inflammatory response?
Integration
Edema fluid with high protein concentration
Exudate
Type of inflammatory cells that secretes interleukin-1?
Monocyte/macrophage
Factors recruiting leukocytes, especially neutrophils, from the vascular compartment into the injured tissue?
Chemotactic factors
Type of exudate characterized by the absence of a prominent cellular response?
Serous exudate
Earliest vascular response to mild skin injury?
Vasoconstriction of arterioles
Emigration of leukocytes adherent to the vascular endothelium?
Diapedesis
Disease caused by hereditary deficiency of NADPH oxidase
Chronic granulomatous disease
Increased number of circulating leukocytes accompanying acute inflammation
Leukocytosis
Adhesion molecules involved in leukocyte recruiment?
Immunoglobulins
The enzyme that directly metabolize arachidonic acid?
Cyclooxygenase
Type of serous exudate containing red blood cells
Serosanguinolent exudate
Force that governs the flow of water due to differences in ion (salt) concentrations?
Osmotic pressure
Activators of the alternative complement pathway
Viruses
Major inflammatory mediator released by mast cells that causes increased vascular permeability?
Histamine
