Inflammation

Question 1

Vascular Endothelial adherence molecules from the selectin family

Answer 1

P selectin., E selectin, GlyCam 1, CD34

Question 2

Leukocyte adherence molecules from the selectin family

Answer 2

Sialyl Lewis X modified proteins

L selectin

Question 3

Vascular endothelial adherence molecules integrins

Answer 3

I CAM 1

VCAM 1

Question 4

Leukocyte adherence molecules integrins

Answer 4

CD11/CD18 INTEGRINS (LFA1, Mac 1)

VLA 4 Iintegrin

Question 5

INTEGRINS major role in neutrophil

Monocytes lymphocytes

Answer 5

Adhesion arrest transmigration

Question 6

INTEGRINS major role in neutrophil

Monocytes lymphocytes

Answer 6

Adhesion arrest transmigration

Question 7

INTEGRINS major role in eosinophils monocytes and lymphocytes

Answer 7

Adhesion

Question 8

Chemotactic agents for neutrophils include

Answer 8

C5a
Arachdonic acid metabolites
Bacterial products
Ltb4 and cytokines

Question 9

Chemotactic agents?

Answer 9

C5a
LTB4
Bacterial components

Question 10

What carb do neutrophils and macrophages recognize on foreign particles

Answer 10

Mannose and fructose

Question 11

Major opsins?

Answer 11

IgG antibody

C3b and C3bi

Question 12

Dangerous products of oxygen reduction

Answer 12

Peroxide anion O2-
Hydroxyl radicals OH-
Singlet oxygen O-

Question 13

Neutrophilia

Answer 13

Pyogenic infection and tissue destruction

Question 14

Eosinophilia

Answer 14

Allergic disorders and parasite jnfection

Question 15

Lymphocytes

Answer 15

Hronic infection, viral infection

Whooping cough

Question 16

Monocytosis

Answer 16

Infectious mononucleosis

Bacterial infections - tuberculosis, typhoid

Question 17

John hunter

Answer 17

In the 18th century was the first to realise that acute inflammation was a beneficial response

Question 18

1880s Ellie metchnikoff discovered

Answer 18

The process of phagocytosis

Question 19

George Bernard shaw..

Answer 19

Created a play the doctors dilemma anout phagocytosis

Question 20

Thomas lewis

Answer 20

Established the concept of chemical mediators of inflammation

Question 21

What are the five types of wbc

Answer 21

Neutrophils eosinophils basophils monocytes lymphocytes

Question 22

What is vascular endothelial cells

Answer 22

They line the inside of arteries and veins

Question 23

Mast cells release

Answer 23

Found in connective tissue and release histamine

Question 24

Endothelial gaps features

Answer 24

Effects 20 to 60 micrometer
Mediated by histamin bradykinin leukotrienes, substance P, C5a, C3a
Myosin contraction
Transient

Question 25

Endothelial cell retraction induced by

Answer 25

IL1, TNF, IFNY RESTRUCTURING OF CYTO SKELETON PROLONGED RESPONSE

Question 26

Leukocyte mediated endothelial injury

Answer 26

Neutrophils Most commonly lungs and glomeruli Immediate sustained

Question 27

Mediators of vascular transcytosis

Answer 27

Vascular endothelial growth factor, | Histamine.