Inflammation & Repair Flashcards
(24 cards)
what is a protective response of the body to injury or invasion of disease?
inflammation
how does inflammation differ from infection?
infection requires pathogenic organism (virus, bacteria…). it can cause inflammation when the pathogenic org release toxins
chemicals, trauma, foreign substances, physical agents (radiation..), pathogenic org (bacteria, fungus..) and allergies can all cause ____?
inflammation
what are physical signs of inflammation
heat, redness, swelling, pain, loss of function
what is the difference b/t an acute and chronic response to inflammation?
acute is rapid onset and last only a short while (e.g. gallstone, hepatitis, gallbladder attack). chronic progresses more slowly and last longer and doesn’t go away.
what does tissue do in response to injury?
releases histamine, bradykinin, chemicals, send RBC’s to site of infection etc
what, when released, causes capillary walls to dilate causing swelling and itchiness (e.g. red blush from burn or insect bite)
histamine
what substance increases blood flow, capillary permeability and incites pain in response to tissue injury?
bradykinin
_____ when released cause vasodilation and increased blood flow to injury causing hyperemia? What are some examples?
chemicals. leukocytes (WBC’s) and neutrophils move blood to injured tissue to destroy bacteria.
what is leukocytosis?
increase in # of WBC’s generally caused by infection
____ is the digestion and ingestion of bacteria and particles.
phagocytosis
What is another name for Kupper Cells
Phagocytes
What are the remnant s of leukocytosis and phagocytosis – a yellowish substance associated w/ bacterial infections causing inflammation? What is it produced from?
Pus. produced from dead neutrophils, exudate and liquified tissue, suppurative (stinky) inflammation (purulen)
___ is the response of tissue in attempt to maintain normal structure and function. (happens in conjunction w/ inflammation)
wound healing, repair and regeneration
what restore integrity to injured tissue
wound healing
what is the gap that is filled w/ blood upon clotting in wound healing?
initial stability
The ____ ___ exudates formation and phagocytosis of wound contaminates and clots.
inflammatory phase of wound healing
What 3 phases happen simultaneously in wound healing?
contraction (2-3 day post injury) reduces size of open defect as much as 70%
repair - wound replaced by scar
regeneration - tissue replaced by identical cells
what factors influence wound healing?
type of wound, contaminates, excessive tissue loss, failure of wound edge to connect, infection, circulation
wound dehiscence, incisional hernia, ulceration, keloid, and contracture are all _____ of wound healing.
complications
bursting of wound due to mechanical stress (vomiting, coughing, ileus -stool obstruction) or systemic factors (poor metabolic status -associated w/ metastatic cancer)
wound dehiscence
what is generally in the abd wall, intestine and/or peritoneum protruding into would of prior surgery?
incisional hernia
what is an abnormal scar formation (can be caused by scratch, scrape or pimple)
keloid
what is the general term for fixed resistance to muscle stretching?
contracture
