Inflammatory Bowel Disease Lecture Powerpoint Flashcards Preview

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Flashcards in Inflammatory Bowel Disease Lecture Powerpoint Deck (14)
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1
Q

Crohn’s disease description***

A

-Inflammation and ulceration (eventually fistula) somewhere along any point of the GI tract (but most often the terminal ileum and right colon) that involves the full thickness of the bowel in a patchy, non-continuous distribution (skip lesions), although the rectum is relativey spared. Chronic recurring condition marked by remissions and exacerbations

2
Q

Crohn’s disease etiology (3)**

A
  • strong genetic component
  • autoimmune response to evironmental factors/bacteria
  • cigarette smoking increases susceptability in genetically susceptible
3
Q

Crohns disease typical presentation (6)

A
  • female
  • urban (processed food)
  • teenage to young adulthood
  • RLQ pain
  • mass effect in the lower abdomen (firmness in intestine)
  • high fever
4
Q

Bloody diarrhea should make you think of ____ and ___ as backup

A

ulcerative colitis, crohns

5
Q

Crohn’s disease often results in…

A

….fistulas (colo-bladder, colo-vaginal, etc.)

6
Q

Pyoderma gangrenosum

A

Cutaneous ulcerations caused by fistula tracts indicative of internal disease of the body

7
Q

Diagnostic test of choice for crohn’s disease and ulcerative colitis (3)

A
  • colonscopy and biopsy (remember patchy lesions with healthy tissue between)
  • EGD
  • barium studies (string sign due to stricture of bowel wall)
8
Q

Lab studies for diagnosis of crohn’s disease (4)

A
  • occult blood
  • ova and parasite
  • stool culture
  • fecal lactoferrin***
9
Q

Tests to help differentiate between crohn’s and ulcerative colitis other than colonoscopy

A

-p-ANCA neg + ASCA = crohn’s

p-ANCA positive 40-80% of the time = UC

10
Q

Ulcerative colitis description

A

Chronic, recurrent condition marked by exacerbations and remissions where inflammation is localized primarily to the mucosa of the colon only and the rectum and is uniform and continuous with bloody diarrhea and tenesmus often as presenting symptoms

11
Q

Ulcerative colitis etiology (3)

A
  • genetic predispostion
  • cigarrette smoking is PROTECTIVE
  • autoimmune
12
Q

Ulcerative colitis typical presentation (4)

A
  • any age
  • more common in industrialized urban areas (processed food)
  • worsening bloody diarrhea
  • bowel shortening on colonsocopy as well as continuous erythema only affecting the mucosa
13
Q

For quick immediate relief of IBD, use these drugs (2)

A
  • prednisone/steroids (IV or PO)

- budenoside

14
Q

Untreated IBD increases risk for…

A

….colon cancer