Inflammatory Bowel Diseases Flashcards
(33 cards)
All of the following are TRUE about IBD EXCEPT:
A. Immune-mediated
B. May be acute or chronic
C. Infantile IBD in children refers to <2 years or age
D. If a patient has IBD, there is a 10% lifetime risk for a first-degree relative to be affected
E. None of the options
E. None of the options
All of the following are TRUE about Ulcerative Colitis EXCEPT
A. Has the highest incidence among 20-29 years old
B. Greatest incidence is among white and Jewish people
C. Female predominance
D. Smoking may prevent the disease
E. None of the options
C. Female predominance
All of the following may increase the risk of IBD EXCEPT:
A. High in animal protein B. High in sugars and sweets C. High in fish and shellfish D. High in omega-6 fatty acids E. High in omega-3 fatty acids
E. High in omega-3 fatty acids
Deficiency of IL-10 and IL-10 receptor is mostly associated with what genetic disorder?
A. Turner's syndrome B. Hermansky-Pudlak C. Wiskott-Aldrich syndrome D. IPEX E. Early-onset IBD
E. Early-onset IBD
Turner's = X chromosome Hermansky=Pudlak = 10q23 WAS = WAS protein Glycogen storage disease = G6P transport protein IPEX = FoxP3
Which of the following genes is considered as risk factor for IBD that is shared with asthma?
A. TNFAIP3 B. IL10 C. ORMDL3 D. IL12B E. IL23R
C. ORMDL3
RA = TNFAIP3 Psoriasis = IL23R, IL12B AS = IL23R Type1 DM= IL10, PTPN2 SLE = TNFAIP3, IL10
Which of the following cells secret interferon gamma?
A. TH cells B. TH2 cells C. TH17 cells D. Two of the options E. All of the options
A. TH1 cells
TH2 = IL-4, IL-5, IL-13 TH17 = IL-17, IL-21
Which of the following is the most common type of UC?
A. Proctitis B. Left-sided colitis C. Distal colitis D. Pancolitis E. Extensive colitis
A. Proctitis
According to the Montreal classification of extent and severity of UC, how do you categorize this:
Inflammation which extends to the proximal splenic flexure and with normal inflammatory markers
A. E1, S1 B. E1, S2 C. E2, S1 D. E2, S2 E. E3, S1
E. E3, S1
When the mucosa is erythematous and resembles sandpaper, how do you categorize the severity of the disease?
A. Mild inflammation
B. Moderate inflammation
C. Severe inflammation
D. None of the options
A. Mild inflammation
Which of the following is the most adverse complication of UC?
A. Colon cancer B. Toxic megacolon C. Colonic perforation D. Massive colon hemorrhage E. Fulminant disease
C. Colonic perforation
Ulcerative colitis’ damage is limited to which of the following?
A. Mucosa B. Superficial submucosa C. Deep submucosa D. Muscularis E. Two of the options F. All of the options
E. Two of the options
Mucosa and superficial submucosa
Which part of the small intestine does Crohn’s disease affects?
A. Duodenum B. Proximal jejunum C. Distal jejunum D. Proximal ileum E. Terminal ileum
E. Terminal ileum = 90%
All of the following are TRUE about Crohn’s disease EXCEPT:
A. Most of the cases involve both small and large intestine
B. Rectum is often spared
C. Continuous lesions
D. May affect any part from the mouth to the anus
E. None of the options
C. Continuous lesions
Which of the following is characteristic appearance of CD?
A. Cobblestone B. Polyps C. Pseudopolyps D. Thin mucosal wall E. Diffuse lesions
A. Cobblestone
All of the following are signs and symptoms found in Mild UC EXCEPT:
A. Nocturnal diarrhea B. Rectal bleeding C. Tenesmus D. Weight loss E. Two of the options F. None of the options
E. Two of the options
Severe = nocturnal/postprandial diarrhea
Moderate to severe = anorexia, nausea, vomiting, fever, weight loss
All features are increased in UC EXCEPT:
A. CRP B. ESR C. Platelet count D. Hemoglobin E. None of the options
D. Hemoglobin
Which of the following complications of UC may be due to underlying neoplasia?
A. Toxic megacolon B. Colonic perforation C. Strictures D. Intractable disease E. Massive colon hemorrhage
C. Strictures
Intestinal malabsorption in jejunoileitis commonly manifests as all of the following EXCEPT:
A. Anemia B. Hypoalbuminemia C. Abetalipoproteinemia D. Hypocalcemia E. Hypomagnesemia
C. Abetalipoproteinemia
Which of the following disease is a cause of niacin deficiency?
A. Pellagra B. Megaloblastic anemia C. Hemolytic uremic syndrome D. Vertebral fractures E. Hemorrhagic steatorrhea
A. Pellagra
Which of the following allows direct visualization of the entire-small bowel mucosa?
A. CT B. MR enterography C. Wireless capsule endoscopy (WCE) D. Ultrasound E. Any of the options
C. Wireless capsule endoscopy (WCE)
All of the following are serological markers for CD EXCEPT
A. ASCA B. pANCA C. Omp-C D. I2 E. Flagellin F. None of the options
B. pANCA
Which of the following dermatologic manifestations of IBD manifests as neutrophilic dermatosis?
A. Erythema nodosum B. Pyoderma gangrenosum C. Sweet syndrome D. Metastatic CD E. Psoriasis
C. Sweet syndrome
This disease is asymmetric, polyarticular, and migratory which mostly affect large joints of UE and LE.
A. Peripheral arthritis
B. Ankylosing spondylitis
C. Sacrolitis
D. Osteoarthropathy
A. Peripheral arthritis
AS = spine and pelvis
Sacrolitis = asymptomatic
This is a disorder characterized by both intrahepatic and extrahepatic bile duct inflammation and fibrosis.
A. Hepatic steatosis
B. Primary sclerosing cholangitis
C. Gall bladder polyps
D. Cholelithiasis
B. Primary sclerosing cholangitis (PSC)
