Inflammatory skin condition Flashcards

Question

Erythema nodosum : Definition

Answer 1

* Hypersensitivity reaction that leads to the inflammation of the subcutaneous fat tissue * Immune mediated - secondary to deposition of immune complexes

Answer 2

1. **Rash** : Red nodules develop on shins * Tender to touch 2. **Distribution** : Shins (most common) 3. **Symptoms** : May have mild fever, malaise and joint pain Prognosis : Self resolves

Answer 3

1 . **Infection** : * Streptoccus * Tuberculosis 2 . **Systemic disease** * Sarcoidosis * Inflammatory bowel disease 3 . **Drugs** } Same as for erythema multiform * Penicillin * Suphonomides e.g. Sulfasalazine * COCP

Answer 4

* Shingles (herpes zoster infection) is an acute, unilateral, painful blistering rash caused by reactivation of the varicella-zoster virus (VZV). * Following primary infection with VZV (chickenpox), the virus lies dormant in the dorsal root or cranial nerve ganglia.

Answer 5

1. **VZV reactivates from sensory nerve ganglia** * Triggered by : Immunosupression e.g. HIV 2 . **Virus replication** : travels down the nerve fibres to the skin * Inflammation of the nerve causes pain and irritation 3 . **Nerve involvement** * Commonly affects T1-L2 dermatome skin 4 . **Skin eruption** * Blistering, painful rash appears along distribution of affected nerve

Answer 6

1 . Appearance : * Erythematous, macular rash over affected dermatome } well demarcated * Becomes vesicular and blisters form 2 . Severe burning pain over sit of skin

Answer 7

**Acyclovir** * Indication : < 72 hours unless patient <50 and has mild truncal rash and no over risk factors 1 . Infectious until lesions crusted over 2 . Analgesia : NSAID or neuropathic agents 3 . Oral corticosteroid : Immunocompromised

Answer 8

1 . Post-herpetic neuralgia } most common * On going neurological pain 2 . Ramsay Hunt syndrome 3 . Herpes zoster opthalmicus * virus affects ocular division of trigeminal nerve

Answer 9

Viral skin infection molluscum contagiosum virus (MCV), a poxvirus

Answer 10

1. small, dome-shaped, 2. flesh-colored papules 3. Central indentation/dimple

Answer 11

1. Highly contagious - avoid sharing towels/contact etc 2. Self resolves

Answer 12

Fungal infection of the scalp Cause : Fungus Trichophyton tonsurans

Answer 13

1. Scaling, flaking of skin 1. Red, inflamed patches 1. Itching 1. Scarring alopecia - hairloss ‘black dot’ appearance

Answer 14

Terbinafine

Answer 15

Fungal infection of body's skin

Answer 16

* Well-defined circular erythematous lesion - centre may clear * Scaling and redness * Itching * Pustules and papules

Answer 17

Oral Fluconozole

Answer 18

* Atheletes foot * Fungal infection, affects **skin between toes**

Answer 19

1. Itching between toes 1. Redness, inflammation 1. Scaling, Peeling

Answer 20

1. Avoid environments of tramission : Communal showers, swimming pools } moist environments

Answer 21

‘Ring worm’ - superficial fungal infection of the skin Refers to : infection of the body only

Answer 22

1. Well demarcated - circular, red, and scaly rash with raised edges 1. Central hypopigmentation

Answer 23

Oral fluconazole

Answer 24

Scabies is caused by the** mite /Sarcoptes scabiei/ ** spread by prolonged skin contact. * typically affects children and young adults.

Answer 25

1. Wide spread pruritus : scratching and excoriation present 2. Linear burrows : side of fingers, between fingers and flexor aspect of wrist

Answer 26

1. All house hold and contacts treated + bedding washed 2. First line : Permethrin 5%

Answer 27

rare, non-infectious, inflammatory disorder. * Caused by dense infiltration of neutrophils * It is an uncommon cause of very painful skin ulceration.

Answer 28

1. Idiopathic 50% 2. inflammatory bowel disease in * ulcerative colitis * Crohn’s 3. Rheumatological * rheumatoid arthritis * SLE

Answer 29

Haemotological cancer * Myeloproliferative, Lymphoma, Myeloid leukaemia (excess neurtrophisl)

Answer 30

1. Lower limbs } most common 2. Start : small red pustule 3. Progress : Painful purple ulcer * Systemic sx : Fever, Myalggia

Answer 31

1. PO Steroids 2. Immunosupression : Ciclosporin

Answer 32

Common yeast infection of the skin, caused by the fungus /Malassezia/

Answer 33

1. Hypopigemented patches (also be hyperpigmented) 2. On the trunk 3. Mild pruritus and scaling

Answer 34

1. Ketoconozole Shampoo - large areas 2. Skin scraping and oral itraconzole

Answer 35

Immune mediated chronic inflammatory condition affecting skin and body

Answer 36

1. Polyglonal papular rash - white line pattern 2. Itchy 3. Soles, palms, and flexor surface of arms 4. Oral involvement common : white laced pattern on buccal mucosa 5. Nail thinning

Answer 37

1. Potent topical steroid 2. Benzydamine mouth wash for oral mucosa

Answer 38

* autoimmune condition causing sub-epidermal blistering of the skin. * This is secondary to the development of antibodies agaisnt trigger.

Answer 39

More common in elderly patients * itchy, tense blisters typically around flexures * No mucusoa ingolvement - seem in pemphigus

Answer 40

1. Referral to Dermatology for Skin biopsy - shows IgG and C4 2. Oral corticosterpods

Answer 41

Acute rash caused by herpes hominis virus 7 Affects young adults

Answer 42

1. Hx of revent iral infection 2. Herald patch - on trunk 3. Erythemaous oval scaly patches running parallael

Answer 43

Self limiting

Answer 44

* irritant contact dermatitis: common - non-allergic reaction * allergic contact dermatitis: type IV hypersensitivity reaction.

Answer 45

Erythema is typical, crusting vesicles are rare

Answer 46

often seen on the head following hair dyes. Presents as an acute weeping eczema Mx : Potent steroid

Answer 47

Skin patch test

Inflammatory skin condition Flashcards

(71 cards)