Inheritance Flashcards

(71 cards)

1
Q

What is a gene?

A

A gene is a unit of inheritance.

Genes are segments of DNA that determine specific traits.

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2
Q

What are alleles?

A

Alleles are different forms of the same gene.

Each allele can result in different traits.

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3
Q

Where do alleles occupy on chromosomes?

A

Alleles occupy the same relative positions/gene loci on a pair of homologous chromosomes.

This is crucial for genetic inheritance.

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4
Q

What does a dominant allele do?

A

A dominant allele expresses itself and gives the same phenotype in both homozygous and heterozygous conditions.

Dominant alleles mask the effects of recessive alleles.

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5
Q

How does a recessive allele express itself?

A

A recessive allele only expresses itself in the phenotype in the homozygous condition.

This means two copies of the recessive allele must be present.

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6
Q

What is codominance?

A

Codominance is a condition where both alleles express themselves equally in the phenotype.

Example: IA and IB alleles in blood group.

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7
Q

Define homozygous.

A

Homozygous refers to an organism that has identical alleles for a particular phenotype/trait.

This results in a consistent expression of that trait.

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8
Q

Fill in the blank: A _______ allele refers to an allele that expresses itself in both homozygous and heterozygous conditions.

A

[dominant]

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9
Q

Fill in the blank: A _______ allele only expresses itself in the phenotype in the homozygous condition.

A

[recessive]

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10
Q

True or False: Codominance results in one allele being dominant over another.

A

False.

In codominance, both alleles are expressed equally.

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11
Q

True or False: Homozygous organisms have different alleles for a specific trait.

A

False.

Homozygous organisms have identical alleles for a trait.

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12
Q

What does heterozygous refer to?

A

An organism that has different alleles for a particular phenotype/trait.

Heterozygous organisms have two different versions of a gene.

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13
Q

Define phenotype.

A

The expressed trait in an organism, such as observable features like eye colour and height.

Phenotype is the result of the interaction between genotype and the environment.

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14
Q

What is genotype?

A

The genetic make-up of an organism.

Genotype refers to the specific alleles an organism possesses.

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15
Q

What is the expected phenotypic ratio when both parents are heterozygous?

A

3:1

This ratio is typically observed in a monohybrid cross of heterozygous parents.

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16
Q

What are the terms used to describe the generations in genetic crosses?

A

F1 generation and F2 generation.

F1 refers to the first filial generation, while F2 refers to the second filial generation.

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17
Q

What is the genotype of the parents in the genetic diagram provided?

A

Tt x Tt

This indicates that both parents are heterozygous for the trait.

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18
Q

Fill in the blank: To obtain an expected ratio of 3:1 in the offspring generation, both parents must be _______.

A

heterozygous

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19
Q

What is required to obtain an expected ratio of 1:1 in the offspring generation?

A

One parent must be heterozygous while the other is homozygous recessive

This is known as a test cross.

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20
Q

How can a test cross help determine if a genotype is homozygous dominant or heterozygous dominant?

A

By crossing with a homozygous recessive. Offspring will show all traits if homozygous dominant, or a 1:1 ratio if heterozygous dominant.

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21
Q

Why do observed ratios often differ from expected ratios?

A

Due to random fusion of nuclei of gametes and small sample size

Smaller numbers of progeny can lead to significant variations in ratios.

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22
Q

What is co-dominance?

A

A condition where both alleles in a heterozygote are fully expressed

An example is blood group AB, which expresses both antigens.

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23
Q

What are multiple alleles?

A

Genes that exist in more than two types of alleles

An example is the ABO blood group system.

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24
Q

What are the three alleles that control blood group?

A
  • I_A
  • I_B
  • I_O
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25
Which alleles are co-dominant in the ABO blood group system?
I_A and I_B ## Footnote Both I_A and I_B express equally in individuals with blood group AB.
26
What is the result of having blood group AB?
Both antigen A and B are present ## Footnote This is due to the co-dominance of I_A and I_B.
27
What chromosome does an egg contribute during fertilisation?
X chromosome
28
What chromosomes can a sperm contribute during fertilisation?
X or Y chromosome
29
How is sex determined in humans?
By the sex chromosome the sperm carries
30
How many pairs of autosomes do humans have?
22 pairs
31
How many pairs of sex chromosomes do humans have?
1 pair (XX/XY)
32
How do you find the probability of 2 traits?
Multiply the probability of each trait together
33
What is the probability of a blood group O child who is a boy born to blood group A and blood group B parents?
0.125
34
Define mutation in the context of genetics.
A change in the structure of a gene or in the chromosome number
35
What is an example of a gene mutation?
Sickle cell anaemia
36
What happens to the gene that codes for normal haemoglobin in sickle cell anaemia?
It is mutated to form abnormal haemoglobin
37
What shape do red blood cells take in sickle cell anaemia?
Sickle shaped
38
What is the consequence of sickle shaped red blood cells?
They carry less oxygen around the body
39
What is the outcome for homozygous recessive individuals in sickle cell anaemia?
They die young
40
What is the outcome for heterozygous individuals in malaria prone areas?
They survive
41
What do heterozygotes carry in terms of alleles?
One mutated allele
42
What is an example of a chromosomal number mutation?
Down syndrome
43
How many chromosomes are present in individuals with Down syndrome?
47 chromosomes
44
Which chromosome has an extra copy in Down syndrome?
Chromosome number 21
45
What is the cause of the extra chromosome in Down syndrome?
Nondisjunction during meiosis
46
What fails to separate during anaphase I or anaphase II leading to Down syndrome?
Homologous chromosomes or sister chromatids
47
What are factors that may increase the rate of mutation?
Radiation and chemicals ## Footnote Includes UV light, gamma rays, and carcinogens like formaldehyde and mustard gas.
48
What type of variation is controlled by the additive effect of many genes?
Continuous variation ## Footnote Examples include skin colour, height, and weight.
49
What type of variation is controlled by one or a few genes?
Discontinuous variation ## Footnote Examples include blood group, gender, eye colour, and the ability to roll tongue.
50
What is a characteristic of continuous variation?
Range of phenotypes ## Footnote Can be affected by environmental conditions.
51
What is a characteristic of discontinuous variation?
Clear-cut phenotypes with no intermediate forms ## Footnote Not affected by environmental conditions.
52
Give an example of continuous variation.
Skin colour, height, weight ## Footnote These traits show a range of phenotypes.
53
Give an example of discontinuous variation.
Blood group, gender, eye colour ## Footnote These traits exhibit distinct categories.
54
Fill in the blank: Continuous variation is affected by _______.
environmental conditions ## Footnote This means factors like nutrition can influence these traits.
55
Fill in the blank: Discontinuous variation is controlled by _______.
one or a few genes ## Footnote This leads to distinct categories in traits.
56
What leads to differential survival and reproduction in organisms?
Variation and competition ## Footnote This concept is central to the theory of natural selection.
57
What are the sources of variation in organisms?
* Crossing over at prophase I during meiosis * Independent assortment at metaphase I during meiosis * Random fertilisation of gametes during sexual reproduction * Mutation in genetic material
58
How does mutation contribute to natural selection?
Mutation provides new alleles to the gene pool for natural selection to act on. ## Footnote New alleles can introduce advantageous traits that enhance survival.
59
Why is genetic variation important for organisms?
It helps organisms adapt and survive in changing environments.
60
What does competition among organisms lead to?
Differential survival and reproduction.
61
What is natural selection?
A process in nature that results in the best-adapted organisms surviving to reproduce.
62
What types of organisms are selected by nature?
* More resistant to diseases * Better adapted to changes in the environment
63
What is a mechanism of evolution?
Natural selection acting on genetic variation in rapidly reproducing organisms.
64
What happens when organisms reproduce rapidly?
They may outpace the food supply, leading to competition.
65
What is the result of spontaneous mutation?
Genetic variation in organisms.
66
What do favorable traits confer to organisms?
A selective advantage.
67
What occurs when species produce more offspring than the environment can support?
Competition for resources and selective pressures.
68
What are examples of artificial selection?
* Production of cows that produce large amounts of milk * Production of corn that contains beta-carotene * Production of new breeds of orchids * Plants with high oil content in seeds * Animals with good meat, high milk production, good quality fur
69
What are some environmental factors that act as forces of natural selection?
* Competition for food * Competition for territory * Climate * Types of predators * Availability of mates
70
What is evolution?
The process by which complex forms of living organisms arise from simpler ancestral forms.
71
What ensures that organisms best adapted to the environment will survive?
Natural selection.