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CYP450 > Inhibitors > Flashcards

Inhibitors Flashcards

1
Q

protease inhibitors

A

3A4 (strong) inhibitor

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2
Q

clarithromycin

A

3A4 (strong) inhibitor

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3
Q

chloramphenicol

A

3A4 (strong) inhibitor

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4
Q

ketoconazole

A

3A4 (strong) inhibitor

2C19 inhibitor

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5
Q

nefazodone

A

3A4 (strong) inhibitor

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6
Q

verapamil

A

3A4 (moderate) inhibitor

1A2 (strong) inhibitor

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7
Q

diltiazem

A

3A4 (moderate) inhibitor

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8
Q

erythromycin

A

3A4 (moderate) inhibitor

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9
Q

fluconazole

A

3A4 (moderate) inhibitor

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10
Q

grapefruit juice

A

3A4 (moderate) inhibitor

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11
Q

valerian

A

3A4 (moderate) inhibitor

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12
Q

norfluoxetine

A

3A4 (weak) inhibitor

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13
Q

cimetidine

A

3A4 (weak) inhibitor
2D6 (weak) inhibitor
2C19 inhibitor
1A2 (weak) inhibitor

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14
Q

buprenorphine

A

3A4 (weak) inhibitor

2D6 (weak) inhibitor

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15
Q

itraconazole

A

3A4 (strong) inhibitor

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16
Q

gabapentin

A

3A4 (weak) inhibitor

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17
Q

pregabalin

A

3A4 (weak) inhibitor

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18
Q

amiodarone

A

3A4 inhibitor
2D6 (weak) inhibitor
1A2 inhibitor

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19
Q

ciprofloxacin

A

3A4 inhibitor

1A2 (strong) inhibitor

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20
Q

voriconazole

A

3A4 inhibitor

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21
Q

mifepristone

A

3A4 inhibitor

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22
Q

imatinib

A

3A4 inhibitor

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23
Q

norfloxacin

A

3A4 inhibitor

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24
Q

delavirdine

A

3A4 inhibitor

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25
Q

fluvoxamine

A

3A4 inhibitor
2C19 (strong) inhibitor
1A2 (strong) inhibitor

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26
Q

star fruit

A

3A4 inhibitor

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27
Q

milk thistle

A

3A4 inhibitor

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28
Q

gingko bilboa

A

3A4 inhibitor

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29
Q

isoniazid

A

3A4 inhibitor
2C19 inhibitor
1A2 inhibitor

30
Q

piperine

A

3A4 inhibitor

31
Q

fluoxetine

A

3A4 (weak) inhibitor
2D6 (strong) inhibitor
2C19 (strong) inhibitor

32
Q

paroxetine

A

2D6 (strong) inhibitor

33
Q

bupropion

A

2D6 (strong) inhibitor

34
Q

quinidine

A

2D6 (strong) inhibitor

35
Q

ritonavir

A

2D6 (strong) inhibitor

36
Q

sertraline

A

2D6 (moderate) inhibitor

37
Q

duloxetine

A

2D6 (moderate) inhibitor

38
Q

terbinafine

A

2D6 (moderate) inhibitor

39
Q

haloperidol

A

2D6 inhibitor

40
Q

perphenazine

A

2D6 inhibitor

41
Q

thioridazine

A

2D6 inhibitor

42
Q

zuclopenthixol

A

2D6 inhibitor

43
Q

risperidone

A

2D6 inhibitor

44
Q

chlorpromazine

A

2D6 inhibitor

45
Q

St John’s Wort

A

2D6 inhibitor

1A2 (moderate) inhibitor

46
Q

diphenhydramine

A

2D6 inhibitor

47
Q

hydroxyzine

A

2D6 inhibitor

48
Q

citalopram

A

2D6 inhibitor

49
Q

escitalopram

A

2D6 inhibitor

50
Q

celecoxib

A

2D6 inhibitor

51
Q

clomipramine

A

2D6 inhibitor

52
Q

cocaine

A

2D6 inhibitor

53
Q

doxorubicin

A

2D6 inhibitor

54
Q

metoclopramide

A

2D6 inhibitor

55
Q

methadone

A

2D6 inhibitor

56
Q

moclobemide

A

2D6 inhibitor

2C19 (strong) inhibitor

57
Q

doxepin

A

2D6 inhibitor

58
Q

cannabidiol

A

2D6 inhibitor

59
Q

topiramate

A

2C19 (weak) inhibitor

60
Q

omeprazole

A

2C19 inhibitor

61
Q

lansoprazole

A

2C19 inhibitor

62
Q

rabeprazole

A

2C19 inhibitor

63
Q

pantoprazole

A

2C19 inhibitor

64
Q

modafinil

A

2C19 inhibitor

65
Q

probenacid

A

2C19 inhibitor

66
Q

herbal teas (peppermint, German chamomile, dandelion)

A

1A2 (moderate) inhibitor

67
Q

caffeine

A

1A2 (weak) inhibitor

68
Q

interferon

A

1A2 inhibitor

69
Q

grapefruit juice

A

1A2 inhibitor

70
Q

cumin

A

1A2 inhibitor

71
Q

tumeric

A

1A2 inhibitor

CYP450 (3 decks)

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