INNATE AND ADAPTIVE IMMUNITY

Question 1

What is clonal expansion?

Answer 1

clone of identical cells in response to binding of specific antigen by surface receptor

Question 2

What is a plasma cell?

Answer 2

produce and secrete large amounts of antibodies

Question 3

What T cells are restricted to MHC class I?

Answer 3

cytotoxic T cells - protecting against virus

Question 4

What T cells are restricted to MHC class II?

Answer 4

Helper CD4 cells - increase humoural immune response

Question 6

What is innate immunity?

Answer 6

First line of defence - skin, mucous, inflammation, granulocytes

Question 7

What is adaptive immunity?

Answer 7

Specific immunity, cells have undergone training to differentiate between self and non self proteins

Question 8

How many types of immunity are involved in adaptive ?

Answer 8

Two - cell mediated and antibody mediated

Question 9

What is cell meditated immunity?

Answer 9

Cytotoxic T cells attack foreign antigens

Question 10

What is antibody mediated immunity?

Answer 10

B cells recognise antigens, activate into plasma cells and create antibodies

Question 11

What does MHC I do during adaptive immunity?

Answer 11

Displays antigens that are internally produced - if there is a virus in the cell, it will display on MHC I surface as a non-self protein, so cells can activate

Question 12

What does MHC II do?

Answer 12

Present in both innate and adaptive - found on cells that are capable of phagocytosis and display on antigen presenting cells