INORGANIC COMPONENT Flashcards

1
Q

• The typical salivary pH of an adult is between

A

6-7.4

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2
Q

what movement stimulated saliva production which allows buffering to take place to restore pH

A

MASTICATION

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3
Q

higher the sucrose conc leads to a

A

fall in pH

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4
Q

urea.. the rate at which pH was restored

A

increased

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5
Q

increased salivary flow rate leads to an

A

increased salivary buffering capacity

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6
Q

bicarbonate ions

A

-produced by striated epithelium of the secretory ducts and the parotid gland

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7
Q

is bicarbonate ions affected by the metabolic activity

A

yes

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8
Q

bicarbonate ions acts as a

A

buffer as pKA value is 6.1

at ph6.1 there are equal concentrations of carbonic acid and carbonate ions

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9
Q

as the salivary pH falls, the .. reaction is favoured

A

forward

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10
Q

flow rate increase, bicarbonate ions

A

increases

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11
Q

potassium and sodium ions are

A

counter ions that preserve electrical neutrality

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12
Q

what direction is sodium pumped as it passes along the intercalated duct of the salivary glad

A
  • actively pumped OUT

- via the sodium-potassium pumps

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13
Q

low salivary rate results in ( affect on Na plus)

A

low Na + concentration

  • so in duct for a longer period
  • more Na + will be pumped out of the fluid
  • so lower concentration
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14
Q

another possible reason for increased na plus concentration

A

damage of the ductal cells

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15
Q

as salivary flow rate increases, the potassium concentrations in the saliva

A

remain constant

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16
Q

increased flow rate affect on mg ions

A

low

17
Q

compare conc of calcium ions in saliva compared to magnesium ion

A
  • higher levels of calcium
18
Q

role of calcium ions

A
  • essential in remineralisation and prevent mineral dissolution
19
Q

affect of flow rate on calcium ions

A

high flow rate, ca2 plus remains relatively constant

20
Q

how does mg concentrations in saliva change as flow rate increases

A

decrease

21
Q

phosphate ions

A

act as a buffer in unstimulated saliva

22
Q

another function of phosphate ions

A

-important in the maintenance of ionic product for hydroxyapatite - inhibit dissolution and crucial for remineralisations

23
Q

affect of flow rate on inorganic phosphate ios

A

high flow rate, low phosphate conc
-as phosphate is actively added to the secretion as it passes through the duct so a faster transit time will results in less phosphate being added

24
Q

why does an increased flow rate result in a more alkaline PH

A
  • due to an increased conc of bicarbonate ions