Inotropic Drugs Flashcards
1
Q
What are inotropic Drugs?
A
- drugs that increase the force of myocardial contraction to combat HF
2
Q
Cardiac Glycosides
A
Digoxin
3
Q
Causes of HF
A
- cardiac muscle defect
- SVT
- CAD
- Hypertension
- valve deficiency
- diabetes
4
Q
Symptoms of HF
A
- reflex tachycardia
- edema
- elevated venous pressure
- dyspnea
- weakness
- enlarged heart (cardiomegaly)
5
Q
Digoxin MoA
A
- Positive Inotropic- strengthens and increases force
- Negative Chronotropic- slows and reduces heart rate
- Negative Dronotropic- slows and decreases AV node conduction
6
Q
Digoxin Effects
A
- increases strove volume
- decrease in venous BP
- increase in coronary circulation
- promotes diuresis
- eases dyspnea, cough, and cyanosis
7
Q
Indications
A
- HF
- supraventricular dysrhythmias (above ventricle)
8
Q
Digoxin Adverse Effects
A
- narrow therapeutic window
- toxicity
- malaise
- anorexia
- nausea
- vomiting
- diarrhea
- colored vision (yellow)
- halo vision
- dysrhythmia
- bradycardia
9
Q
Causes of Digoxin Toxicity
A
- diarrhea
- change in renal function
- low K
- elderly
- hypothyroid
- ginko/ st john’s wart
10
Q
Digoxin Immune Fab Therapy
A
- antidote binds to digoxin
11
Q
Digoxin Interactions
A
- amphotericin B
- furosemide
- thiazides
- laxitives
- steroids
- anticholinergics
- quinidine
- verapamil
12
Q
Watch for…
A
- apical pulse under 60 bpm or over 120 bpm (less than 90 in infant)
- serum labs (K)
- anorexia
- nausea
- vomiting
- diarrhea
- blurred vision
- green or yellow halos around objects
13
Q
Chronotropic
A
rate of heartbeat
14
Q
Dromotropic
A
speed of electrical impulses
