Integument Flashcards

1
Q

What is the name of the growth phase of hair?

A

Anagen

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2
Q

What is the name of the shedding phase of hair?

A

Telogen

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3
Q

What happens if the anagen phase of hair growth is shorter than the telogen phase?

A

Hair will be shedded faster than it grows, leading to hair loss

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4
Q

How does hypothyroidism affect hair growth?

A

Causes anagen phase to be shorter and telogen to be longer - hair loss/bilateral alopecia

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5
Q

Where does the synthesis of keratin filaments occur?

A

Stratum basale

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6
Q

How does hard keratin differ to soft keratin?

A

Soft - elastic (e.g. skin)

Hard - contains more sulphur, less elastic, more permanent (e.g. nails, horns)

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7
Q

What is the function of sebaceous glands?

A
  • oil glands
  • produce sebum
  • empty into a hair follicle
  • not associated with thermoregulation
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8
Q

What are the two main components of sebum?

A
  • Dead epithelial cells

- Lipids

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9
Q

What are some of the functions of sebum?

A
  • helps prevents water loss
  • lubricates skin
  • inhibits bacteria growth
  • help spread sweat
  • oils hairs
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10
Q

What regulates sebaceous glands?

A

Sex steroid hormones

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11
Q

Which sweat glands are involved in thermoregulation in the skin?

A

Apocrine

Ecrine

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12
Q

What cells do both apocrine and ecrine glands contain?

A

Myoepithelial cells

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13
Q

Which species rely most on sweat glands for thermoregulation?

A
  • Horses and donkeys
  • Cattle
  • Humans
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14
Q

What are some other specialised skin glands found throughout different species?

A
  • anal sacs of cats and dogs
  • interdigital pouch of the sheep
  • infraorbital pouch
  • tail gland
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15
Q

Why is the production of melanin important?

A
  • Camouflage
  • Mimicry
  • Social communication
  • Protects against solar radiation
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16
Q

How is melanin secreted from melanocytes?

A
  • Melanin is synthesised and packed into vesicles
  • Vesicles are transferred into keratinocytes
  • when keratinocytes reach the surface of the skin melanin is shed
17
Q

Which hormone controls melanin synthesis?

A

MSH = melanocyte-stimulating hormone

18
Q

What is the production of MSH stimulated by?

A
  • UV light
  • Disease states
  • Other external signals e.g. camouflage
19
Q

Vitamin D is important in the homeostasis of what?

20
Q

What is photosensitivity?

A
  • abnormal reaction to sunlight due to accumulation of photosensitive compounds below the skin
21
Q

What does an animals temperature depend on?

A

The balance between heat input and heat output

22
Q

Which 3 anatomical structures make up the ‘core’?

A

Brain, thorax and abdomen

23
Q

Where is temperature change detected?

A

Hypothalamus receives information from internal and external thermoreceptors

24
Q

Where are warm and cold receptors located?

A
Warm = dermis
Cold = epidermis
25
What can be stimulated at very cold or hot temperatures?
Nociceptors = pain receptors
26
What are some motor output adaptations to cold stress?
- behaviour - reduced skin blood blow - shivering - activation of brown fat - hormone secretion
27
Which nervous system regulates blood flow to the skin?
Sympathetic
28
Which change in nerve impulse frequency causes vasodilation?
Decreased frequency
29
How is panting different to respiration?
- rapid and shallow - no respiratory gas exchange - little energy expended
30
How does shivering increase heat production?
- Skeletal muscle produces heat when it contracts
31
What is a brown fat cell?
A skeletal muscle cell with no actin or myosin
32
What causes non shivering thermogenesis?
Increased activity of the sympathetic nervous system
33
What are pyrogens/their role?
Some systemic illnesses increase the hypothalamic set point to higher than normal value
34
List the mechanisms a pig will use to regulate its temperature on a hot day
- Drink more, eat less - Wallow - Open posture - Seek shade - Move less - Vasodilation – they do not sweat
35
Why are surgical patients at risk of hypothermia?
- not moving - increased SA - losing heat through incision/prep
36
How does an adult animals LCT and TNZ compare to that of an neonate?
Lower LCT and wider TNZ