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D1F U3 Histology > Integumentary System > Flashcards

Integumentary System Flashcards

1
Q

Avascular, keratinized stratified squamous epithelium layer of skin is ______.

Derived from _____

A

Epidermis

Ectoderm

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2
Q

Highly vascular, connective tissue layer of skin is _____.

derived from ______

A

Dermis

Mesoderm

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3
Q

Adipose tissue layer deep to skin

A

Hypodermis/Subcutaneous layer

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4
Q

Hairless skin found on palms and soles only?

Number of layers?

A

Thick skin

5

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5
Q

Skin with hair follicles?

Number of layers?

A

Thin Skin

4

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6
Q

Epidermis layers (deep to superficial)

A
  1. Stratum Basale
  2. Stratum Spinosum
  3. Stratum Granulosum
  4. Stratum Lucidum (thick skin only)
  5. Stratum Corneum

“Bad Sprinters Get Leg Cramps”

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7
Q

Keratinocytes (___%) produce ____ and form a _____.

A

85%

Keratins

Water Barrier

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8
Q

Melanocytes (__%) produce _____ that are made and stored in _____.

These rounded cell bodies are in the _____ and the long processus extend between keratinocytes in the ______

A

5%

Melanin (pigment)

Melanosomes

Stratum Basale

Stratum Spinosum

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9
Q

Langerhans’ cells (__%) are _____ cells

A

2-5%

Antigen-presenting

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10
Q

Merkel’s Cells (__%) are ____ cells

A

6-10%

Mechanoreceptor

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11
Q

Keratins form filaments called ____/_____/_____

A

Keratin filaments

Intermediate Filaments

Tonofilaments

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12
Q

Keratinocytes participate in formation of water barrier via production of _____

A

Lamellar Bodies

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13
Q

Mitotically active layer of epidermis (stem cells -> keratinocytes); production of intermediate (keratin) filaments begins here

A

Stratum Basale

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14
Q

Cytoplasmic processes for attachment via desmosomes in this epidermis layer called ______.

Intermediate filaments here are grouped into bundles called _____.

Production of _____ and _____ also begins in this layer.

A

Stratum Spinosum

Tonofibrils

Keratohyalin Granules
Lamellar Bodies

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15
Q

This epidermis layer known as _____ is intensely basophilic.

It contains _____ that bundle tonofilaments into tonofibrils

Here, conversion of granular cells into cornified cells happens (AKA ____)

____ are also release here.

A

Stratum Granulosum

Keratohyalin Granules

Keratinization

Lamellar Bodies

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16
Q

Cells are sloughed off at this epidermal layer known as _____

A

Stratum Corneum

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17
Q

Accumulates over keratinocyte nuclei to protect DNA from UV radiation

A

Melanin

18
Q

Langerhans’ Cells are found within the _____ and derived from ____

A

Stratum Spinosum

Bone marrow

19
Q

Merkel’s Cells are located within the ____ and form ____ with afferent nerve fibers

A

Stratum Basale

Merkel’s Corpuscle

20
Q

Most common skin cancer. Slow growing tumor. Resembles cells of stratum basale.

A

Basal Cell Carcinoma

21
Q

Second most common skin cancer. Highly atypical cells at all epidermis levels.

A

Squamous Cell Carcinoma

22
Q

Most serious skin cancer. Melanocyte origin. Irregularly pigmented, multicolor lesion.

A

Malignant Melanoma

23
Q

Loose connective tissue layer of Dermis known as ____ with finger-like protrusions known as _____

A

Papillary Layer

Dermal Papillae

24
Q

Dense irregular connective tissue Dermis layer

A

Reticular Layer

25
Q

Ovoid structures found in dermis and hypodermis?

Contains a myelinated nerve ending surrounded by a capsule consisting of _____.

Function?

A

Pacinian Corpuscles

Concentric Lamellae

Detects pressure/vibration

26
Q

Meissner’s Corpuscles are located within dermal papillae of _____.

Flattened ____ form lamellae.

Function?

A

Hairless skin

Schwann cells

Detect light touch

27
Q

Smooth muscle that causes hair to stand on end (goosebumps).

____ innervation

Function?

A

Arrector Pili Muscle

Sympathetic

Insulation

28
Q

Apocrine and Eccrine glands are both _____ secretion types

A

Merocrine (exocytosis)

29
Q

Temp regulation and waste removal gland

A

Eccrine Sweat Gland

30
Q

This gland is stimulated during emotional stress and sexual excitement

A

Apocrine Sweat gland

31
Q

This gland is found throughout most skin, especially forehead/palms/soles

A

Eccrine Sweat Gland

32
Q

This gland is found in skin of axilla, perineal, beard regions

A

Apocrine Sweat glands

33
Q

This Sudoriferous Gland is found mostly in deep dermis

A

Eccrine Sweat Gland

34
Q

This Sudoriferous gland is found mostly in subcutaneous layer

A

Apocrine Sweat gland

35
Q

This Sudoriferous gland secretes to the surface of epidermis

A

Eccrine Sweat Gland

36
Q

This Sudoriferous gland secretes into hair follicle

A

Apocrine Sweat Gland

37
Q

This Sudoriferous gland produces viscous, protein-rich sweat

A

Apocrine Sweat Gland

38
Q

This Sudoriferous gland begins function soon after birth

A

Eccrine Sweat Gland

39
Q

This Sudoriferous gland functions during/after puberty

A

Apocrine Sweat Gland

40
Q

Body odor results from _____

A

Surface Bacterial breakdown of apocrine sweat

41
Q

This gland is found everywhere but thick skin because it secretes into hair follicles. Involved in acne development.

Type of secretion?

A

Sebaceous (Oil) Gland

Holocrine (apoptosis) secretion of sebum

D1F U3 Histology (6 decks)

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