Intercellular Signaling (homework questions) Flashcards
(21 cards)
Secreted by glands into capillary and has target organs reached by blood
Endocrine
Secreted by neurons into capillary and has target organ reached by blood
Neuroendocrine
Released by axon terminals of neurons into the synaptic junction, acts locally
Neurotransmitters
Secreted by cells into extracellular fluid and effects neighboring cells of a different type
Paracrine
Secreted by cells into extracellular fluid affects the function of the same cells that produced them
Autocrine
Which biochemical class of endocrine molecules is stored in secretory vesicles?
Proteins and polypeptides
Which biochemical class of endocrine molecules needs a transport plasma protein to travel in the blood?
Steroid
Which biochemical class of endocrine molecules binds to a nuclear or cytoplasmic receptor for its function?
Steroid
What is the name of the class of endocrine molecules derived from the amino acid tyrosine?
Catacholamines
Which hormone, derived from an AA, acts like a steroid?
Thyroid hormone
Name the three polypeptide growth factors
- Mitogens
- Trophic factors
- Chemoattractants
What do mitogens do?
Stimulate cell proliferation (mitosis)
What do trophic factors do?
Growth & survival
What do chemoattractants do?
Gradient for mobile (WBC) cells (inflammation)
What cells produce histamine?
Mast cells
Where are mast cells located?
CT of bronchi and intenstines
What is the function of the H1 histamine receptors in venules?
Causes venules to vasodilate, increasing tissue swelling and WBC infiltration into the tissue
Name the location of the H2 histamine receptor
Stomach
What is the mechanism of action for the release of stomach acid?
Histamine binds to H2 receptors in the stomach
What AA is necessary to form nitric oxide?
Arginine
What enzyme does nitric oxide turn on?
Nitric oxide synthase
