Intervention Cardiology and Cardiac Surgery Flashcards
(29 cards)
Percutaneous coronary intervention
- Formerly known as coronary angioplasty with stenting
- Non-surgical procedure that uses a catheter and balloon to place a stent to open up blood vessels in the heart that have been narrowed by plaque buildup.
two types of stents
•Bare Metal Stents •Drug Eluting Stents
endarterectomy
Surgical removal of part of the inner lining of an artery, any obstructive deposits
•(Usually atherosclerotic plaques)
•Most often performed in the carotid artery or femoral arteries
Treatments for arrhythmias
- temporary epicardial pacer
- pacemaker
- Implantable cardioverter defibrillator (ICD)
Temporary epicardial pacer
- Epicardial pacing wires common after open heart surgery wires exit through mediastinal incision.
- Cardiac surgery makes myocardium irritable and prone to arrhythmia
- Pacer is used to control heart rate due and rhythm.
Median sternotomy approach
- Coronary artery bypass graft CABG
* Valve Replacement or repair•Mitral (MVR) or Aortic (AVR)•Heart Transplant
Thoracotomy approach
- Lobectomy
* Lung Transplant (Bilateral aka “Clamshell” for COPD)
Transcatheter aortic valve replacement approach
accessed through femoral artery
minimally invasive cardiac surgery approach
- CABG, valvular surgery
Video assisted thoracic surgery approach
- lobectomy (lung cancer)
Median sternotomy
- One of the most frequent accesses in cardio-thoracic surgery
- Vertical inline incision is made along the sternum.
- Chest wall is retracted Mediastinum exposed
Coronary artery bypass graft
- First done 1967
- 320,00 bypasses per year done in US
- 1-2% mortality rate although 5-10% risk of MI during procedure
- Graft vessels sewn to coronary arteries beyond blockage and attached to aorta
- Triple, quadruple or quintuple bypasses are now routine
- Most commonly used vessel for grafts is saphenous vein.
CABG procedure
- CABG surgery takes ~4hours to complete.
- Aorta is clamped off for about 60 minutes to allow bloodless field and allow bypasses to be connected to aorta.
- Heart is stopped using a chilled K+ solution
- Plastic tubes are placed in RA to channel venous blood out of the body for passage through heart lung machine
- Body is supported by cardiopulmonary bypass for about 90 minutes.
- Sternum is wired together with stainless steel and the chest incision is sewn closed.
- Breathing tube removed shortly after surgery.
- Chest tubes left in place to allow drainage of any remaining blood from the space around the heart (mediastinum)
- Patients usually get out of bed and are transferred out of ICU day after surgery
- ~25% of patients develop heart rhythm disturbances within the first 3-4d post-op.
- Temporary a-fib related to surgical trauma to the heart.
- Most resolve one month after surgery
Left Internal Mammary artery grafts
- Gaining popularity especially for LAD - Proximal origin off left subclavian maintained and distal end is separated from the chest wall,
- Remain open longer (90% in 10yrs) - compared to 66% of vein grafts, - also maintain endothelial function
- Internal mammary arteries generally not used for emergency CABG surgery
Disadvantages of LIMA
- Limited lengthof vessel
- May prolong surgery
- Risk of sternal wound failure
Intra-aortic balloon pump
- Most common circulatory assist device in critically ill patients with cardiac disease - (HF usually).
- Improves ventricular performance of a failing heart by facilitating an increase in myocardial oxygen supply and a decrease in myocardial oxygen demand
- Inflates at the onset of diastole, increasing diastolic pressure and thus increases in coronary blood flow and which improves myocardial oxygen supply.
- Deflates just before systole, thus reducing LV afterload, which decreases demand and improves cardiac output.
Cardiac transplantation (HTx)
- End-stage heart failure
- Cardiomyopathy (48%)
- CAD (44%)
- Congenital
- Valvulardefect
- Retransplant
- Other
Indications for cardiac transplant
- Cardiogenic shock requiring continuous inotropic support or mechanical support
- Persistent NYHA functional class IV symptoms refractory to treatment
- Intractable angina
- Intractable life-threatening arrhythmias
- Congenital heart disease with NYHA III/IV symptoms refractory to treatment
Absolute contraindications of cardiac transplant
- Irreversible Pulmonary vascular resistance
- Malignancy
- Active infection
- HIV/AIDS
Relative contraindications of cardiac transplant
- Age>65*
- Poorly Controlled DM with organ damage/failure
- Psychosocial impairment that jeopardizes transplanted heart
- Arnold Palmer and VA Example
- Cigarette smoking
- Unreliable Caregivers
Donor allocation system
•Supervised by United Network of Organ Sharing (UNOS)
- Private organization designed to ensure equitable distribution of organs
- Organ Procurement and Transplantation Network (OPTN)
- Divided into 11 regions
- Prioritization based on •Severity of illness
- Geographic Distance from Donor
- Patient time on wait list
cardiac transplant procedure
•Median sternotomy •Cardiopulmonary bypass
Physiological changes post transplant
- Transplanted heart is denervated
- Higher resting HR (90-110bpm)
- Absence of direct neural regulation of HR/SV
- HR and SV controlled via circulating catecholamines and muscle pump
- Absence of chest pain
Exercise capacity post transplant
- 56% of patient exercise capacity is <70% of predicted normal
- Only 13% achieve >90% predicted normal
- Contributing Factors
- Transition from type 1 to type 2 fibers - Especially for patients with previous long standing HF
- Neuro-hormonal changes from long standing HF resulting in elevated TPR
- Side effects of corticosteroids and immunosuppressive therapy