Intracranial haemorrhage Flashcards

1
Q

Name the 3 types of spontaneous intracranial haemorrhage

A
  • Subarachnoid haemorrhage
  • Intracerebral haemorrhage
  • Intraventricular haemorrhage
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2
Q

What is subarachnoid haemorrhage (SAH)?

A
  • Bleeding into the subarachnoid space
  • Potentially fatal if missed
  • Even with treatment 46% 30 day mortality
  • Usually underlying berry aneurysm
  • Sometimes AVM or no underlying cause found
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3
Q

How does SAH present?

A
  • Sudden onset severe headache
  • Collapse
  • Vomiting
  • Neck pain
  • Photophobia
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4
Q

What would be the differential diagnoses of sudden onset headache?

A

SAH, migraine, benign coital cephalgia

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5
Q

What are the clinical signs of SAH?

A
  • Neck stiffness
  • Photophobia
  • Decreased conscious level
  • Focal neurological deficit - dysphasia, hemiparesis, CN III palsy
  • Fundoscopy - retinal or vitreous haemorrhage
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6
Q

What would a CT scan show in SAH?

A
  • May be negative if >3 days post ictus
  • Negative in 15% of patients who have bled
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7
Q

What would be present in the CSF if a lumbar puncture were performed for a patient with a SAH?

A
  • Safe to perform in alert patient with no focal neurological deficit and no papilloedema or after normal CT scan
  • Bloodstained or xanthochromic CSF (6-48 hour)
  • Differentiate from traumatic tap
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8
Q

How is cerebral angiography performed in SAH?

A
  • Seldinger technique via the femoral artery
  • Digital subtraction 4 vessel angiography with multiple views
  • Gold standard but occasionally may miss an aneurysm due to vasospasm
  • MR and CT techniques increasingly used
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9
Q

What are some of the complications of SAH?

A
  • Re-bleeding - 20% risk in first 14 days, 50% in first 6 months
  • Delayed ischaemic deficit
  • Hydrocephalus
  • Hyponatraemia
  • Seizures
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10
Q

What is delayed ischaemia and how is it treated?

A
  • Delayed ischaemic neurlogical deficit occurs days 3-12 after SAH
  • Altered conscious level or focal deficit
  • Vasospasm
  • Treatment:
    • Nimodipine
    • High fluid intake ‘Triple H therapy’ (hypertension, hypervolaemia, haemodilution)
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11
Q

What is hydrocephalus and how is it treated?

A
  • Increased intracranial CSF pressure
  • 6% symptomatic - increasing headache or altered conscious level
  • Often transient
  • Treatment - CSF drainage - LP, EVD, shunt
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12
Q

What is the cause of hyponatraemia in SAH and how is it treated?

A
  • SIADH - syndrome of inappropriate anti-diuretic hormone release
  • Often transient
  • Do not fluid restrict
  • Supplement sodium intake
  • Fludrocortisone to treat
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13
Q

What is the risk of seizures associated with SAH?

A

3% acute risk, 10% 5-year risk

Anti-convulsant prophylaxis

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14
Q

What is the prognosis in patients with SAH?

A
  • 10% die at scene
  • 20% die in first week
  • 50% die in first month
  • 50% of survivors have major disability
  • 66% of successful patients never return to their previous occupation
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15
Q

What is an intracerebral haemorrahge?

A
  • Bleeding into the brain parencyhma
  • 50% secondary to hypertension
  • 30% due to aneurysm or AVM
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16
Q

What causes hypertensive intracerebral haemorrhage?

A
  • Charcot-Bouchard microaneurysms arising on small perforating arteries
  • Basal ganglia haematoma
17
Q

How do ICHs present?

A
  • Headache
  • Focal neurological deficit
  • Decreased conscious level
18
Q

What investigations are done in ICH?

A
  • CT scan - urgent if decreased conscious level
  • Angiography if suspicion of underlying vascular anomaly
19
Q

How are ICHs treated?

A
  • Surgical evacuation of haematoma +/- treatment of underlying abnormality
  • Non-surgical management
20
Q

What is the prognosis for ICH?

A
  • Good if small superficial clot and good neurological status
  • Poor if large basal ganlgia or thalamic clot with major focal deficit or deep coma
21
Q

What is an intraventricular haemorrhage?

A
  • Occurs with rupture of a subarachnoid or intracerebral bleed into a ventricle
  • Any combination of subarachnoid, intracerebral and interventricular haemorrhage can occur
22
Q

What are AVMs and how do they present?

A
  • Arterio-venous malformations - usually intraparenchymal
  • Seizures
  • Haemorrhage - intracerebral, subarachnoid or subdural
  • Headache
  • Steal syndrome
23
Q

How are AVMs treated?

A
  • Surgery
  • Endovascular embolisation
  • Stereotactic radiotherapy
  • Conservative
  • Weigh risks against benefit