Intracranial Regulation Flashcards
What does drug choice for seizures depend on
the type of seizures that the patient has
Partial (focal) seizures
involved one area of the brain and does not spread throughout
Generalized seizures
begin in one area of the brain and rapidly spread throughout the hemispheres
What drugs treat generalized seizures
hydantoins, barbiturates, benzodiazepines
Example of a hydantoin
phenytoin
Example of a barbiturate
phenobarbital
Example of a benzodiazepine
diazepam
Why is important to monitor serum levels of seizure drugs
to have the correct therapeutic effect for the patient, the drug needs to be in its therapeutic range
When are shorter half-life drugs used
emergent situations
When are longer half-life drugs used
maintenance treatment
What do seizures and antiseizure agents affect in children
learning and social development
What are children more sensitive to with antiseizure agents
sedating effects
How does metabolism differ in children than adults
drugs are absorbed and metabolized faster in children
How does drug dosage differ between children and adults
children require a higher dose per kg than adults (NOT A HIGHER DOSE THAN ADULTS)
What are children monitored for with the use of antiseizure agents
drug effects, serum levels, switching of drug and dose occur often
