Intraoperative Neurophysiological Monitoring Flashcards

(32 cards)

1
Q

What is intraoperative monitoring?

A
  • Continuous, on-line electrophysiologic assessment, measurement, and interpretation of neural responses to intraoperative events
  • Modality-specific, controlled stimulation during the course of surgery
  • Assesses the integrity of a sensory (CN VIII) or motor (CN VII) modality during a surgical procedure
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2
Q

What is the audiologist’s job during IOM?

A
  • Administer and interpret electrophysiologic measurements of neural function including:
  • Sensory and motor evoked potentials
  • Tests of nerve conduction velocity
  • Electromyography

-These measurements are useful in differential diagnosis, pre- and post-operative evaluation of neural function, and neurophysiologic IOM of CNS, spinal cord, and cranial nerve function

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3
Q

What are indications for IOM?

A
  • When there is a risk of surgical complications involving the CNS or PNS
  • When surgical or anesthesia intervention (indicated by monitoring) could help prevent, reverse, reduce consequences
  • PURPOSE: to improve post-operative by correlating changes in neurophysiological responses with intraoperative responses
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4
Q

Describe the pre-operative assessment.

A

1) Pre-op audiologic workup
- Audiogram
- Immittance
- OAEs
- Speech discrimination
- Auditory electrophysioloy

2) Pre-incision ABR/ECochG
- Check equipment
- Identify any noise
- Patient baseline

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5
Q

What personnel should be in the operating room?

A
  • Surgeon
  • Anesthesiologist
  • Nurses
  • Audiologist
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6
Q

Describe the electrical and magnetic environment of the operating room.

A
  • Operating microscope
  • Anesthesia machine
  • Pulse oximeter machine
  • Electroacutery machine
  • Automated blood pressure machine
  • Heart rate monitor
  • Respirator rate monitor
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7
Q

What are some hearing preservation strategies?

A
  • Cerebellopontine angle tumor removal
  • Vestibular nerve resection
  • Microvascular decompression of CN V or CN VII
  • Cochlear implantation (electric ABR and facial nerve)
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8
Q

What types of damage could occur in the operating room?

A
  • Mechanical: compression, tearing, cutting, stretching
  • Ischemic: interrupted blood supply to cochlea or brainstem
  • Thermal: electrocautery
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9
Q

What are the three surgical approaches?

A

1) Retrosigmoid (suboccipital)
2) Translabyrinthine
3) Middle Fossa

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10
Q

Describe the retrosigmoid surgical approach.

A
  • Craniotomy is made behind the ear in the occipital bone
  • Bone overlying the IAC is removed to expose and remove the tumor
  • Best candidates: patients with tumors that do not involve the lateral 1/3 of the IAC and do not impinge on the brainstem
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11
Q

What are advantages of the retrosigmoid surgical approach?

A
  • Allows removal of tumors of different sizes
  • Offers the possibility of hearing preservation
  • Approach offers the surgeon a wide view of the cisternal component of the tumor and thus good access to the root entry zone of the acoustic nerve
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12
Q

What are disadvantages of the retrosigmoid surgical approach?

A
  • Necessity for cerebellar retraction
  • Less access to the facial and cochlear nerves in the distal IAC
  • Increases the potential to leave a residual tumor fragment behind
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13
Q

Describe the translabyrinthine surgical approach.

A
  • Craniotomy is made through the ear in the mastoid bone
  • SCCs are removed to expose the tumor in the IAC
  • Because the canals are removed, complete hearing loss occurs in the affected ear
  • Use: patients who already have hearing loss or when preservation of hearing is not possible
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14
Q

What are advantages of the translabyrinthine surgical approach?

A
  • Size of the tumor not a limiting factor
  • It offers early identification of the facial nerve in the auditory canal
  • There is absolutely no need for cerebellar retraction
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15
Q

What are disadvantages of the translabyrinthine surgical approach?

A

-No hearing preservation

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16
Q

Describe the middle fossa surgical approach.

A
  • Craniotomy is made above the ear in the temporal bone

- Bone overlying the IAC is removed to expose and remove the tumor

17
Q

What are advantages of the middle fossa surgical approach?

A
  • Exposes the IAC and its contents from a superior trajectory
  • Chosen for small tumors located primarily within the IAC
  • Offers the possibility of hearing preservation
  • Excellent approach for small tumors that predominantly occupy the IAC with a minor component in the cistern (usually < 10 mm)
  • Provides exceptional access to the lateral end of the canal
18
Q

Compare far- and near-field recordings.

A

1) Far field: ABR, ECochG
- ABR tracks amplitude and latency of waves I-V
- ECochG tracks N1

2) Near field: Auditory Nerve-Compound Action Potential (AN-CAP)
- AN-CAP tracks P1 and N1

19
Q

Describe P1 and N1 in the AN-CAP.

A
  • P1: depolarizing front of AP as it approaches the electrode
  • N1: AP as it passes over the electrode
20
Q

Describe CN VIII Monitoring: Stimulus.

A
  • Goal is to obtain the largest, most reliable response
  • Transducers: inserts (seal with ear with bone wax or bioclusive patches)
  • Stimulus: clicks
  • Stimulus intensity: 70-95 dB nHL
  • Stimulus rate: as high as possible (limited by sampling rate); odd (minimize 60 Hz noise)
21
Q

Why are benefits of using inserts for CN VIII IOM?

A
  • Better placement to reduce stimulus artifact
  • Reduces contamination by external acoustic noise
  • Minimizes risk for noise-induced hearing loss
22
Q

Why are clicks used for CN VIII IOM?

A

-Broad spectrum stimuli to assess the integrity of the system

23
Q

Describe CN VIII Monitoring: Recording.

A
  • Goal is to optimize speed and SNR
  • Electrodes: subdermal (ABR), peri-tympanic or promontory/transtympanic (ECochG)
  • Filter: 100-3000 Hz
  • Amplifier: differential (common mode rejection)
  • Gain: 75,000-100,000x
  • Artifact reject: on
  • Signal averaging: variable (usually < 10 ms)
24
Q

What should be monitored during CN VIII IOM?

A

1) ABR/ECochG
- Absolute latencies (I, III, V)
- Interwave latencies (need wave I as a reference; indicator of neural conduction time)

2) AN-CAP
- Amplitude (# active ANFs)
- Loss of N1 suggests asynchronous firing and/or conduction block

25
What are potential threats to hearing during CN VIII IOM?
- Fluid in the EAC/ME (conductive component) - Mechanical displacement of the nerve - Misplaced electrodes (especially for ECochG)
26
What should the audiologist communicate to the surgeon regarding CN VIII IOM?
-Any significant changes in response, such as: - Prolongation in latency - Obliteation of waveforms - Severe reductions in amplitude - Appearance of abnormal activity
27
What factors influence the auditory evoked potential during IOM?
1) Pharmacological agents - EX: Isoflurance, Lidocaine - Wave V amplitude reduction - Absolute latency delay - Prolongation of wave I-V interpeak latency 2) Temperature - Decrease in body temp below 35 degrees C (95 degrees F) results in a prolongation of absolute and interwave latencies and a decrease in amplitude of all waves
28
What knowledge should audiologists have in the OR?
- Basic neurophysiology - General human neuro/anatomy and physiology - Clinical neurophysiology (EPs, EEG, EMG, etc.) - Recording neurophysiological signals in the OR - Anesthesia effects - Surgical neuro/anatomy - Surgical procedures that utilize IOM
29
How is CN VII IOM performed?
- Continuous monitoring of ongoing EMG of CN VII | - Use of electrical or mechanical stimulation to obtain a compound facial muscle action potential
30
What stimulus is used during CN VII IOM?
- Direct electrical stimulation of CN VII (0.1-0.2 mA at 4 pulses/s) - OR mechanical stimulation
31
Describe CN VII IOM recording.
- Electrodes: subdermal (Cz, lateral orbicularis oculi, orbicularis oris) - Filters: HP: 5-30 Hz; LP: 2000-3000 Hz - Response latency usually < 20 ms - Automatic muting devices (aka artifact rejection) are often available on some machines
32
What factors may influence facial nerve monitoring?-
- Local anesthetics: delayed latencies and reduced amplitudes due to impaired propagation of potentials - Neuromuscular blockers: spontaneous, free running and evoked responses may be abolished for lengthy periods