Intravenous therapy. P&P cp 40 & Lewis cp 19 (w1&2) Flashcards
(109 cards)
what is intracellular fluid (ICF)/ cytosol?
includes fluid w/in body cells (accounts for approx 60% of body fluid)
what is extracellular fluid (ECF)?
all fluid that is outside the cell and is divided in three compartments:
- interstitial fluid
- intravascular fluid
- transcellular fluid
what is interstitial fluid?
fluid between cells, and outside the blood vessels
-includes lymph
what is intravascular fluid?
is blood plasma
what is transcellular fluid?
separated from other fluids by epithelium
- includes cerebrospinal
- pleural
- peritoneal
- synovial fluid
- and fluids in the gastrointestinal tract
what does passive transport include?
- osmosis
- diffusion
- filtration
what is osmosis?
movement of water through a semipermeable membrane from an area of lower concentration of solute to a higher concentration of solute
what is osmotic pressure?
the pressure needed to counter the movement of water (solvent) across a semipermeable membrane from a low concentration to a high concentration of solutes
what are the 3 main classes of plasma proteins?
albumin, globulins, and fibrinogen
what pressure does albumin produce?
it exerts colloid osmotic pressure or oncotic pressure.
-oncotic pressure tends to keep fluid in the intravascular compartment by pulling water from the interstitial space back into the capillaries
what is diffusion?
movement of ions and molecules in a solution across a semipermeable membrane from an area of high concentration to an area of low concentration
how is the rate of diffusion affected?
by molecule size, concentration, and temperature of a solution
what is active transport?
it facilitates movement of molecules (solutes) across the plasma membrane across a concentration gradient using chemical energy (ATP)-adenosine triphosphate)
what is primary active transport?
a protein binds with a solute to carry it against a concentration gradient. there are three pumps
- uniport
- symport
- antiport
- the sodium-potassium pump (NA/K ATPase) is an antiport pump (transport solutes in the opposite direction across the plasma membrane)
what is filtration?
results of hydrostatic and colloid osmotic pressure
-a passive process whereby water moves into and out of the capillaries
what is hydrostatic pressure?
the force exerted by fluids w/in a compartment
what are the primary hormones that regulate fluid in our bodies?
- antidiuretic hormone
- angiotensin II
- natriuretic peptides
fluid output occurs with which four of our organs (water loss)?
- kidneys
- skin
- lungs
- gastrointestinal tract
what is sensible water loss?
includes water loss through urine and feces
what is insensible water loss?
a continuous, gradual loss of water from the respiratory and skin epithelium
- this water loss may increase in response to changes in respiratory rate and depth
- water loss from skin is regulated by our SNS activating sweat glands
- fevers may increase insensible water loss
what is paco2?
- is partial pressure of carbon dioxide
- measures how well the lungs are excreting CO2 by cells
- high PaCO2 indicates CO2 accumulation in blood (more carbonic acid) caused by hypoventilation; decreased PaCO2 indicates excessive CO2 excretion (less carbonic acid) through hyperventilation.
what does HCO-3 do?
HCO3– is concentration of the base (alkaline substance) bicarbonate, a measure of how well the kidneys are excreting metabolic acids. Increased HCO3– indicates that the blood has too few metabolic acids; decreased HCO3– indicates that the blood has too many metabolic acids.
what does Pa02 do?
PaO2 is partial pressure of oxygen (O2), a measure of how well gas exchange is occurring in the alveoli of the lungs. Values below normal indicate poor oxygenation of the blood.
what is the goal of intravenous fluid therapy?
- maintain fluid, electrolyte, and energy demands when pt’s are limited in their intake
- to prevent or correct fluid and electrolyte disturbances from excess losses