Intro Flashcards

(52 cards)

1
Q

Branch of pharmacology used to treat

A

Pharmacotherapeutics

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2
Q

Branch of pharmacology that studies how the drug affects the body (mechanism of action and biochemical and physical affects)

A

Pharmacodynamics

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3
Q

Branch of pharmacology that studies hoe the body acts on the drug ie absorption, distribution, metabolism, and excretion

A

Pharmacokinetics

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4
Q

Branch of pharmacology that studies natural sources of the drugs or where it comes from

A

Pharmacognosy

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5
Q

Branch of pharmacology that studies toxicity and adverse reactions related to medication

A

Toxicology

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6
Q

Drug evaluation phase where they use human trials with healthy volunteers

A

Phase 1

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7
Q

Drug evaluation phase where they test on people with the disease or health condition the drug is made for

A

Phase 2

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8
Q

Name of medication derived from chemical name in lower case letters

A

Generic or official name

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9
Q

Name of medication based on chemical composition and molecular structure (Not usually seen*)

A

Chemical name

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10
Q

Drug legislation that ordered food and drugs to require labelling; came about because of “moonshine”

A

Pure food and drug act of 1906

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11
Q

Drug legislation that mandated testing for toxicity and established recalls

A

FDA (Food, Drug, and Cosmetics Act of 1938)

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12
Q

Drug legislation that specified ways for drugs to be labelled and prescribed

A

Durham-Humphreys Amendment of 1951

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13
Q

Drug legislation that mandated drugs made safer and tightened control

A

Kefauver-Harris Amendment of 1962

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14
Q

Drug legislation that mandated that high use drugs be given a schedule and also classified drugs for risk of abuse

A

Comprehensive Drug Abuse Prevention and Control Act (Controlled Substances Act)

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15
Q

Drug legislation that says when an uncommon disease becomes to expensive the government may give incentives to continue treatment

A

Orphan Drug Act of 1983

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16
Q

Category of Controlled drug:

High abuse potential: no medical use (ex heroin or other illegal drugs)

A

Schedule I

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17
Q

Category of Controlled drug:

High abuse potential: accepted medical use (ex morphine or Ritalin)

A

Schedule II

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18
Q

Category of Controlled drug:

Low to moderate dependence; low amounts of opioid (ex Codeine or Vicodin)

A

Schedule III

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19
Q

Category of Controlled drug:

Low abuse potential; prescription needed (ex Valium, Phenobarbital, Ambien, Xanax)

A

Schedule IV

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20
Q

Category of Controlled drug:

Low abuse potential; may have small amounts of controlled substances (ex Lomotil or cough medicine)

A

Schedule V

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21
Q

Where would you expect to find scheduled or controlled substances in the hospital?

22
Q

What must be done when throwing away a controlled medication?

A

Nurse must prove with a witness that a drug has been “wasted”

23
Q

What type of drugs can hide or mask important symptoms?

A

OTC drugs like tylenol

24
Q

What is a major disadvantage of using over-the-counter (OTC) medications?

A

People may choose an OTC that interacts with another medication.

25
Which would the nurse identify as a factor in the distribution of a drug?
solubility protein binding blood flow
26
Which phase of drug development is associated with continual evaluation of the drug?
Phase IV
27
Why should the physician order the medications using the generic name instead of a brand name?
Numerous brand names may exist for the same drug, so the generic drug should be ordered
28
Which agency evaluates drugs that have completed phase III?
Food and Drug Administration (FDA)
29
What term is used to describe drugs identified by their chemical or official name in order to be independent of any manufacturer’s assigned name?
generic
30
Why should the nurse write the generic name on the order sent to the pharmacy?
There is less chance of the wrong drug being given, because trade names can be similar.
31
One of the phases of drug development is the post-marketing surveillance phase. Which activity is carried out during this phase?
Health care providers report adverse effects to FDA.
32
Why would the nurse document the generic, rather than proprietary or trade, names of the resident's current drugs?
There is a potential for confusion and miscommunication if proprietary names are used.
33
The nurse is preparing a medication that is new to the market and cannot be found in the nurse's drug guide. How should the nurse obtain the most reliable information about this medication?
Read the package insert.
34
A nurse is administering a large number of medications to a diverse group of clients. What types of drugs will be excluded from these medications?
schedule I
35
A nurse is teaching the client about the use of over-the-counter (OTC) drugs. Which statement best informs the client about their safe use?
“OTC drugs need to be taken with caution; they can mask the signs and symptoms of an underlying disease and interfere with prescription drug therapy.”
36
Which is an example of a black box warning by the Food and Drug Administration (FDA)?
Difficulty breathing and maintaining an airway
37
What is included in FDA approval of a drug for OTC availability?
evaluation of evidence that the consumer can use the drug safely, using information on the product label
38
Genetic engineering allows scientists to produce human insulin by altering which type of bacteria?
Escherichia coli
39
During a phase II study, a drug may be removed from testing because of:
unacceptable adverse effects.
40
Lock and Key Theory; Place where drug binds to receptor
Receptor site
41
Drug mechanism where the drug selectively kills bacteria without killing the host
Selective toxicity
42
OTC drug that vasodilates and relieves pain
Tylenol
43
Drugs that initiate physiological response
Agonist
44
Drugs that block response
Antagonist
45
Drug mechanism that binds to enzyme; inhibits or activates enzyme
Drug-Enzyme
46
When a drug has to go through several systems before it is absorbed or targets, causing lower effects
First pass effect
47
A large dose of drugs pushed first prior to a normal dose to increase effects
Loading dose
48
Range where a drug will be effective
Therapeutic index
49
Amount of drug needed for desired effect
Drug potency or critical concentration
50
Amount of time drug takes to be absorbed by body when taken by mouth
60 minutes
51
Problems with kidneys can lead to....
drug toxicity
52
Types of drug that passes the blood brain barrier
lipid soluble