intro Flashcards

1
Q

what response is responsible for fever

A

innate

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2
Q

response for memory

A

adaptive

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3
Q

Haematopoiesis

A

formation of white and red blood cells

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4
Q

granulocytes

A

basophils
neutrophils
eosinophils

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5
Q

what does bone marrow produce during immune response

A

neutrophils which [hagocytose by using granules or oxidative burst

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6
Q

what do granules fuse with

A

phagosome to form phagolysosome

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7
Q

what do granules contain

A

molecules that lower the ph of the phagolysosome making it very acidic whcih kills some pathogens

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8
Q

oxidative burst

A

when the neutrophil keeps swalloing pathogens it produces highly reactive oxygen species

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9
Q

action of reactive oxygen species

A

destroy proteins and nucleic acids within phagolysosome; pathogen eliminated

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10
Q

what do eosinophils stain

A

pink with eosin

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11
Q

what type of cells are eosinophils

A

phagocytic

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12
Q

eosinophils best known for

A

fighting helminths and in allergic reactions

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13
Q

what do basophils stain

A

blue with hematoxylin

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14
Q

are basophils phagocytic

A

no

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15
Q

what do basophils contain

A

histmaine

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16
Q

what are importannt in initiating allergic repsonses

A

basophils due to having histamine

17
Q

mast cells

A

live in tissues no blood
non phagocytic

18
Q

what releases cytokines

A

monocytes, macrophages and dendritic cells

19
Q

cytokines

A

molecules which attract other immune cells to area

20
Q

where do monocytes circulate

21
Q

what happens to monocytes when they migrate into tissues

A

turn into macrophages

22
Q

where are macropjages found

23
Q

immature dendritic cells

A

good at phagocytosing

24
Q

mature dendritic cell

A

when it phagocytosis’

25
action of dendritic cells
breaks up pathogen contents into short amino acids then moves to nearets lymph mnode and present antigen to t cells
26
what connects innate with adaptive
dendritic cells presnting to t cells
27
priming
when t cell wtih specific receptor to antigen of denrittic cell binds
28
how do denritic cells present to t cells
on a mhc molecule
29
where do b and natural killer cells mature
bone marrow
30
where do some lymphoid progenitor cells migrate
to thymus where they develop into t cells
31
NK cells
large lymphocytes with granules
32
how do nk cells kill their target cells
by releasing cytotocic granules
33
can b cells present antigens to t cells
yes on mhc 2
34
how are b cells matured into plasma cells
by t cells post b cells have presented antigens to them
35
CD4T cells
helper t cells antigen presented on mhc 2 molecule
36
cd8+
cytoxic t cells presented by Mhc 1
37
what can nk cells target
viruses and cancer cells
38