Intro Flashcards

1
Q

gram + and gram - differ by their….

A
  • cell wall structure
    • cell wall has thick peptidoglycan
  • cell wall has thin peptidoglycan and is a unique outer membrane
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2
Q

acid fast staining is used to detect….

A

mycobacterium (TB and leprosy)

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3
Q

most common endospores?

A
  • bacillus

- clostridium

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4
Q

bacterial cell walls are made up of….

A

peptidoglycan (n-acetyl muramic acid and n-acetyl glucosamine which are gram negative) some also have teichoic acid which make it gram positive

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5
Q

Gram - cell wall contains….

A
  • lipopolysaccharide (endotoxin)
  • this signals immune system
  • contains Lipid A and O antigen
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6
Q

Small molecules and ions can cross gram - cell wall via….

A

porins

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7
Q

What bacteria lack a cell wall?

A
  • mycoplasma (variable shape, small organisms)

- PCN will not work bc pcn works on cell wall degradation

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8
Q

amphitrichous
lophotrichous
peritrichous

A
  • single polar flagella on opposite sites (2 on each side)
  • multiple polar flagella on opposite sites
  • flagella distributed over entire cell
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9
Q

Pili that allow surface attachment are termed

A

fimbriae

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10
Q

What are plasmids?

A
  • circular, supercoiled dsDNA (extrachromosomal DNA)

- related to antibiotic resistance

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11
Q

Chromosome forms the nucleoid, which is….

A

single circular double stranded DNA

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12
Q

Cytoskeleton

A

-internal protein framework

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13
Q

Storage granules

A
  • accumulations of polymers

- glycogen, poly-B-hyrdroxybutyrate

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14
Q

Gas vesicles

A

-controlled to provide buoyancy

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15
Q

Main example of a metachromatic granule?

A

Corynebacterium diptheriae

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16
Q

Shape of strep

17
Q

shape of staph

A

grape like cluster

18
Q

cocci

19
Q

bacilli

20
Q

how do bacteria divide?

A

binary fission

21
Q

Lag Phase
Log phase
stationary phase
death phase

A
  • no growth occurs
  • growth rate exceeds death rate, production of primary metabolites
  • growth rate equals death rate
  • death rate exceeds growth rate
22
Q

psychrophiles
mesophiles
thermophiles
halophilic

A

-5 to 15
25-45
45-70
salt loving

23
Q

aerobic
anaerobic
microaerophilic
facultative

A
  • O2
  • CO2
  • requires low O2 concentrations
  • both
24
Q

acidophiles vs

alkaliphiles

A

pH<5.5

pH>8.5

25
icosahedral virus shape and examples
- made up of equilateral triangles | - polio, rhino, adeno
26
capsid
protein layer that surrounds and protects nucleic acids made up of capsomeres
27
enveloped virus structure and examples
- icosahedral or helical structure surround by a lipid bilayer - flu, hep C, HIV
28
helical virus structure adn example
- has a capsid w/ a central cavity | - tbacco mosaic virus
29
function of bacteriophage/phage
-virus that attacks bacteria and injects nucleic acids without going into the cell directly
30
virion
- completely assembled, infection virus outside its host | - whole virus goes into the cell
31
how are retroviruses replicated?
indirectly through a DNA intermediate using a reverse transcriptase enzyme (RNA to DNA)
32
Neuraminidase cleaves ( ) from the cell surface
sialic acid, facilitating viral release from infected cell
33
Hemagluttinin
molecule on virus surface that bonds with sialic acid
34
H1/H2/H3 do what?
-find particular sugars in the respiratory tract
35
What is antigenic drift?
- mechanism for variation in viruses - accumulation of mutations within genes that code for antibody binding site that were originally targeted against the present strain, making it easier for the virus to spread - results in new H/N