Intro Flashcards
(27 cards)
Autonomic Nervous System
Basic Life Functions; subconsciously…NOT muscular movements.
Sympathetic Nervous System
STRESS response, fight or flight (i.e. beta ablockers block this to decrease htn)
Pharmacology
Late 1600s and then 1800s is when drug regulations began… “A science that draws on information from multiple disciplines.
Nursing Process
Assess, diagnose, plan, Intervention, Evaluate.
Two most important properties of an ideal drug…
Safety and Efficacy.
…additional Properties of an Ideal Drug
- Rapid predictable response
- Convenient Administration (po)
- Once a day (short term…b/c more compliance)
- Inexpensive
- Eliminated quickly
- Few drug-drug interactions
- Specificity
Goal of drugs?
Maximum benefit with minimum harm. *Risk Benefit
Anticoagulants
Blood Clotting
Antihyperlipidemics
Lower blood cholesterol
Antihypertensives
Lower blood pressure
Antidysrhythmics
Restore normal cardiac rhythm
Antianginals
Treat Angina (chest pain caused by reduced blood flow to the heart)
Diuretic
Lowers plasma volume
Calcium Channel Blocker
Blocks heart calcium channels (dec. how hard heart squeezes)
Angiotensin-converting enzyme inhibitor
Blocks hormonal activity
Adrenergic antagonist (blocker)
Blocks physiological reactions to stress
Vasodilator
Dilates peripheral blood vessels
Therapeutic vs. Pharmacologic
WHY vs. HOW
Bioavailability
Amount of drug that body has to use and how quickly body can use that. This can be affected by generic vs. trade.
Drug Standards
**Purity and Strength.
FDA
medical devices, herbal products, cosmetics….medications, vet drugs, radiation, tobacco products… BUT NOT AS STRICT AS MEDICATION.
Drug Development
KNOW….phases.
Preclinical research
Non-human lab research…in order to get “investigative new drug” (IND) approval.
Phase 1
SAFETY. (days-weeks and 30-50 people) Healthy males, 150-180 lbs, no medical history. Not if drug works, checking SAFETY.
