Intro To Chem Path Flashcards
(21 cards)
What is chemical pathology?
Chemical pathology is the study of the biochemical basis of a disease, the biochemical application and the molecular diagnostic techniques.
What are the roles of Chemical Pathology in healthcare?
- Diagnosis.
- Screening.
- Prognosis.
- Monitoring.
What is diagnosis?
Diagnosis refers to differentiating between several possibilities of a disease or ailment through using the patient’s initial history or examinations.
What is screening?
To screen for the presence of a particular disease in an otherwise healthy population.
What is Prognosis?
It refers to the prediction of disease susceptibility by observing health trends.
What is monitoring?
Refers to check a disease progression or response to treatment.
What are fluoride oxalate tubes used for?
To prevent erythrocyte glycolysis using us blood glucose
How do you prevent Bilirubin and B-carotene from photo degrading?
By putting them in aluminum foil.
Factors to consider when taking a blood sample.
- Venostasis
- Posture of patient
- Site of venipuncture
Changes that occur in the blood after collection.
- Diffusion of K+, lactase dehydrogenase, asparate transaminase through the red blood cells into the serum/plasma.
2.Decrease in glucose concentration due to erythrocyte glycolysis.
- Photo degradation of Bilirubin and B-carotene when expose to light.
What is limit of linearity?
The maximum reading ability, or the accuracy limit of a machine past which it cannot provide a value.
What is analytical sensitivity?
Refers to the ability to smallest amount or concentration of an analyte that can be detected.
What is analytical specificity?
The ability to test for a particular analyte.
What is precision?
Precision is when a set of values fall within a similar range of values.
What is accuracy?
When a value is the exact or similar to the value that is wanted.
What is clinical sensitivity?
Records the accurate number of people with a particular disease.
What is clinical specificity?
The accurate number of people without the disease.
What are positive and negative predictive values?
The extent to which TP is positive and TN is negative.
What is clinical validation.
It follows technical validation and examine the probability of that an analytically correct result is accurate and useful for the patient.
What is a delta check?
Involves cross checking a patient’s results against previous results to spot unusual changes to ensure patient safety.
What is a range check?
Looks at the value for an analyte, to determine whether the result is physiologically possible.
