Intro to Derm Flashcards
(108 cards)
Dermis
- Connective tissue (collagen and elastin)
- Blood supply
- Nerve supply
- Contains pilosebaceous, apocrine and eccrine structure
- Cellular components: Fibroblasts, mast cells/macrophages, enzymes
- Layers: Reticular (strength, structure elasticity) and - Papillary (supplies nutrients to epidermis, regulates temp)
Epidermis Layers
- Stratum basale (basemnet menbrane)
- Stratum spinosum
- Stratum granulosum
- (Stratum lucidum)
- Stratum corneum (surface layer, dead keratinocytes)
Melanocytes
- Sandwiched between keratin forming cells in basal layer
- Make pigment
- Major component of melanocytic nevi
Merkel cells
- Located in basal layer
- Help with touch sensation
Langerhans cells
- Immune cells scattered throughout the epidermis
- Antigen presenting/ recognition
Appendages
- Cornified (Hair, nails)
- Arrector Pilli (muscle connected to hair to stand it up)
- Glandular (Sebaceous- make sebum, Apocrine- pharemones, Eccrine- make sweat)
Macule
Flat lesion <1 cm
Patch
Flat lesion >1 cm
Papule
Raised lesion < 1 cm
Plaque
Raised lesion >1 cm
Nodule
Raised lesion, firm to the touch, deep seeded
Tumor
Swelling caused by abnormal growth of tissue either benign or malignant
Vesicle
raised, serous (clear) fluid filled, < 1 cm
Bulla
Serous filled lesion > 1 cm
Wheal
Area of edema within the skin, irregularly shaped, transient
Pustule
Pus filled, raised
Scale
thin flake of dead exfoliated epidermis
Excoriation
linear or punctuate erosions caused by scratching
Fissure
A linear crack in the skin often resulting from excessive dryness
Crust
Dried residue of skin exudates such as serum, pus, or blood
Erosion
non-scarring loss of superficial epidermis. Surface is moist but does not bleed. Ruptured vesicle
Ulcer
Deeper loss of epidermis and dermis. May bleed and scar
Scar
connective tissue that arises from injury (keloid- hypertrophic scarring that extends beyond the initial injury)
Atrophy
Thinning of the dermis or epidermis causing depression in the skin (Atrophic scar- thinning, sunken in scar)