Intro to Virology

Question 1

protein shell, or coat, that encloses the nucleic acid

genome

Answer 1

Capsid

Question 2

morphologic units seen in the electron microscope on
the surface of icosahedral virus particles; represent
clusters of polypeptides

Answer 2

Capsomeres

Question 3

a virus particle that is functionally deficient in some

aspects of replication

Answer 3

Defective virus

Question 4

lipid-containing membrane that surrounds some virus
particles; acquired during viral maturation by a
budding process through a cellular membrane

Answer 4

Envelope

Question 5

virus-encoded glycoproteins or projections exposed

on the surface of the envelope

Answer 5

Peplomers

Question 6

the protein-nucleic acid complex representing the

packaged form of the viral genome

Answer 6

Nucleocapsid

Question 7

the basic protein building block of the coat; also

known as protomer

Answer 7

Structural units

Question 8

single folded viral polypeptide chain

Answer 8

Subunit

Question 9

the complete virus particle; serve to transfer the viral

nucleic acid from one cell to another

Answer 9

Virion

Question 10

very small viruses with a particle size of about 18-

26 nm

Answer 10

Parvoviruses

Question 11

example of parvoviruses

Answer 11

HPV B19

Question 12

most well-known among
polyomaviruses; causes progressive multifocal
leukoencephalopathy

Answer 12

JC virus

Question 13

wart” viruses which can cause genital cancer

Answer 13

Papillomaviruses

Question 14

some types can persist in lymphoid tissue
• some cause acute respiratory disease,
conjunctivitis, and gastroenteritis

Answer 14

adenoviruses

Question 15

cause acute and chronic hepatitis

Answer 15

hepadnaviruses

Question 16

oral and genital

lesions

Answer 16

HSV 1 & 2

Question 17

infectious mononucleosis

and assoc with human neoplasms

Answer 17

Epstein-Barr virus

Question 18

Assoc. with Kaposi

sarcoma

Answer 18

Human herpesvirus 8

Question 19

tend to produce vesicular skin

lesions

Answer 19

poxviruses

Question 20

example of poxviruses

Answer 20

smallpox, vaccinia,

molluscum contagiosum

Question 21

Include the torque teno viruses

Answer 21

Anelloviruses

Question 22

picornaviruses that infect humans

Answer 22

entero
rhino
hapato

Question 23

causes hepatatis A

Answer 23

Hepatovirus

Question 24

Associated with gastroenteritis in humans and

animals

Answer 24

astroviruses

Question 25

Similar size to picornaviruses but particles display | a distinctive star-shaped outline on their surfaces

Answer 25

Astroviruses

Question 26

cause of epidemic acute | gastroenteritis

Answer 26

Norwalkvirus

Question 27

Cup-shaped depression on the surfaces of the | particles

Answer 27

Caliciviruses

Question 28

Human Hepatitis E virus Small prticles (27-34 nm), ether resistant, ssRNA, lacks genome-linked protein (VPg) Similar to calicivirus

Answer 28

Hepeviruses

Question 29

Reovirus that cause gastroenteritis and has a distinct wheel shaped appearance

Answer 29

Rotavirus

Question 30

(Colorado tick fever virus)

Answer 30

Coltivirus

Question 31

examples of Togaviruses

Answer 31

Alphavirus, Rubella virus (no arthropod | vector), Eastern equine encephalitis virus

Question 32

Mature virions of these virus accumulate within the cisternae of the ER

Answer 32

Flaviviruses

Question 33

Yellow fever virus, Dengue virus, Zika | virus, Hepatitis C virus is included

Answer 33

Flaviviruses

Question 34

virions incorporate host cell ribosomes during maturation, giving the particles “sandy” appearance

Answer 34

Arenaviruses

Question 35

Example:Lassa fever

Answer 35

Arenaviruses

Question 36

Have petal-shaped projections arranged in a fringe

Answer 36

Coronaviruses

Question 37

MERS COV and SARS are an example of this virus

Answer 37

Coronaviruses

Question 38

Round or filamentous particles with surface projections that contains hemagglutinin or neuraminidase activity

Answer 38

Orthomyxoviruses

Question 39

Envelope is acquired by budding in the Golg

Answer 39

Bunyaviruses

Question 40

Cause hemorrhagic fevers and neuropathy as | well as severe pulmonary syndrome

Answer 40

Hantaviruses

Question 41

Transmitted by persistently infected rodents (not by arthropods) via aerosols of contaminated excreta

Answer 41

Hantaviruses

Question 42

Unique among nonsegmented, negative sense | RNA viruses

Answer 42

Bornaviruses

Question 43

Resembling a bullet, flat at one end and round at | the other

Answer 43

Rhabdoviruses

Question 44

Cause acquired-immunodeficiency syndrome | AIDS

Answer 44

Retroviruses

Question 45

Similar to orthomyxovirus but larger

Answer 45

Paramyxoviruses

Question 46

Example: Mumps, measles, parainfluenza, metapneumo, and respiratory syncytial virus (RSV)

Answer 46

Paramyxoviruses

Question 47

Examples:Marburg and Ebola viruses

Answer 47

Filoviruses