Introduction Flashcards
1
Q
What is the guideline used for chemo
A
NCCN
National comprehensive cancer treatment
2
Q
Cell cycle
A
G1— S——G2——M
Make enzymes—- dna synthesis—— rna and protein—- mitosis
3
Q
Drugs working in cell cycle
G1 s g2 m
A
G1
S: 5-FU, mtx, 6mp, xeloda
G2: etoposide, irenotecan
M: vinca, taxanes
4
Q
Problems with chemo
A
CINV, BMS ( thrombocytopenia, anemia, leukopenia) , TLS, peripheral neuropathy
5
Q
Treatment of CINV ——- sequence: 1234567
A
1 serotonin antagonist
2 corticosteroids
3 nk1 antagonist
4 cannabinoids
5 dopaminergic ant
6 antihistamine
7 benzos
6
Q
What are the 2 off label drugs for cinv
A
Benzos # 1
Olanzapine # 2
