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MTLE: Clinical Chemistry > Introduction > Flashcards

Introduction Flashcards

1
Q

It refers to the discipline involved in selection, provision, and interpretation of diagnostic testing that uses primarily sample from patients.

A

Laboratory Medicine

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2
Q

It refers to the systematic study of biochemical process associated with health and disease and the measurement of constituents.

A

Clinical Chemistry/Medicinal Chemistry/Chemical Pathology

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3
Q

Laboratory medicine is used for confirmation of a clinical suspension [True or False]

A

True

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4
Q

Laboratory Medicine excludes diagnosis [True or False]

A

True

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5
Q

Laboratory Medicine does not provide prognosis [True or False]

A

False

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6
Q

Specimens are ________ and substances are ________.

A

analyzed, measured

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7
Q

These are non functioning wastes products in the process of being cleared in the body.

A

Metabolites

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8
Q

Laboratory request that must be done within 1 hour.

A

STAT

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9
Q

Laboratory request that must be done within 2 hours.

A

Priority

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10
Q

Non urgent and special requests that must be performed within 4-6 hours.

A

Routine tests

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11
Q

It refers to the “Total Quality Control”

A

QA

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12
Q

It is a comprehensive set of policies and procedures.

A

QA

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13
Q

QA monitors quality performance starting from ________ and ends with ________.

A

Ordering of a laboratory determination; Application to patient care

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14
Q

Percentage of errors done by non-laboratory personnel in Pre-analytical phase

A

29%

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15
Q

Pipetting and preparation of PFF (Phase)

A

Analytical Phase

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16
Q

Centrifugation and separating or aliquoting of plasma (Phase)

A

Pre-analytical

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17
Q

Record keeping (Phase)

A

Analytical

18
Q

Incubation of mixture (Phase)

A

Analytical

19
Q

Reference ranges (Phase)

A

Post-analytical

20
Q

It is concerned with the analytical phase of QA

A

QC

21
Q

Assay of control sample (QA or QC)

A

QC

22
Q

Instrument maintenance (QA or QC)

A

QC

23
Q

Statistical Data Analysis (QA or QC)

A

QC

24
Q

Proficiency Testing Survey (QA or QC)

A

QC

25
Q

The proportion of individuals with that disease that test positively with the test

A

Diagnostic Sensitivity

26
Q

The proportion of individual that will test negatively in the absence of disease

A

Diagnostic specificity

27
Q

Ability to measure accurately one component in a specimen without interference

A

Analytical specificity

28
Q

Ability to detect small differences in the concentration of a component in a series of specimens

A

Analytical Sensitivity

29
Q

Easy to predict (Linear pattern)

A

Systematic errors

30
Q

Easy to spot (outlier)

A

Random error

31
Q

Solutions with known characteristics, value, and amount that is used to calibrate an assay method.

A

Reference material

32
Q

A control material should be stable and sufficient to last at least _______?

A

1 year

33
Q

Why are controls be available in convenient vial volumes?

A

To prevent cross contamination

34
Q

They should be lyophilized and should be reconstituted before use

A

Control specimens

35
Q

Most preferred source of control that should be sufficient for one year

A

Pooled control sera

36
Q

The pooled control sera should be analyzed for how many times before obtaining the mean value for each constituent and standard deviation

A

At least 20 times

37
Q

Source of commercial control sera

A

Human serum or bovine (can’t be used in IHC, Dye-binding techniques, and certain bilirubin assay)

38
Q

Type of control that easily deteriorates and hazardous

A

Pooled control sera

39
Q

It refers to the mean and true value

A

Accuracy

40
Q

It refers to the reproducibility under identical conditions

A

Precision

MTLE: Clinical Chemistry (3 decks)

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