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Introduction Flashcards

1
Q

DNA viruses

A

HHAPPPPy
1. Herpes
2. Hepadna
3. Adeno
4. Pox
5. Parvo
6. Papilloma
7. Polyoma

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2
Q

Enveloped DNA viruses

A

Pox, Herpes, Hepadna

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3
Q

Properties of DNA viruses:

Biggest

A

Poxviridae

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4
Q

Properties of DNA viruses:

Only virus that replicate in the cytoplasm

A

Poxviridae

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5
Q

Properties of DNA viruses:

Brick-shaped enveloped (non-icosanedral)

A

Poxviridae

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6
Q

Properties of DNA viruses:

Heaviest

A

Herpesviridae

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7
Q

Properties of DNA viruses:

Lightest

A

Parvoviridae

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8
Q

All DNA viruses are enveloped, except

A

PAPP smear
(Parvo-, Adeno-, Papilloma-, Polyomavirus)

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9
Q

All DNA viruses are dsDNA except

A

parvovirus

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10
Q

All DNA viruses are linear except

A

PoHPa (Polyoma-, Hepadna-, Papillomavirus)

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11
Q

All DNA viruses have icosahedral capsids except

A

poxvirus

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12
Q

All DNA viruses replicate in the nucleus except

A

poxvirus

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13
Q

RNA respiratory viruses

A
  1. Paramyxoviridae
  2. Orthomyxoviridae
  3. Coronaviridae
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14
Q

All RNA viruses are enveloped except

A

CPR (+H ) or PRC examination

Calci-, Picorna-, Reovirus+Herpesvirus

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15
Q

All RNA viruses are ssRNA except

A

Reovirus

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16
Q

All RNA viruses are icosahedral capsids, except for few helical viruses

A

A HELYX

A - Arenavirus
H – Rhabdovirus
E – Emperor’s wear crown “corona”-virus
L – DeLtavirus, FiLovirus
Y – BunYavirus
X – orthomyXo- and paramyxovirus

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17
Q

All RNA viruses are linear except 3 circular ones:

A

• Arenavirus – arenas are round
• Bunyavirus – bunions are round
• Deltavirus – the Greek letter “6” round

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18
Q

All RNA viruses have replicate in the cytoplasm except:

A

Orthomyxo and Retrovirus

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19
Q

virus particle consist of a nucleic acid genome (DNA or RNA)

A

Virion

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20
Q

interaction of a virion with a specific receptor site on the surface of a cell.

A

Attachment

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21
Q

Examples of Viral attachments:

Rhinovirus

A

VP1-VP2-VP3 complex

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22
Q

Examples of Viral attachments:

Adenovirus

A

Fiber protein

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23
Q

Examples of Viral attachments:

Influenza A virus

A

HAgp

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24
Q

Examples of Viral attachments:

Measles Virus

25
Examples of Viral attachments: HIV
gp120
26
Examples of Viral receptors: EBV
C3d Complement Receptor (CR2,CD21) Tc: B cell
27
Examples of Viral receptors: HIV
CD4 Tc: T Helper Cells
28
Examples of Viral receptors: Influenza A virus
Sialic acid Tc: Epithelial Cells
29
Examples of Viral receptors: B19 Parvovirus
Erythrocyte P antigen Tc: Erythroid precursor
30
process where virus attaches to the wall of a cell and is absorbed into the cell through phagocytosis.
Viropexis (Picorna-, Papilloma-, Polyomavirus)
31
normal process used by cell for the uptake of receptor-bound molecules
Endocytosis (hormones, LDL, and transferrin)
32
is the physical separation of the viral nucleic acid from the outer structural components of the virion so that it can function.
Uncoating
33
assembled as procapsids to be filled w/ genome (picornavirus) or assembled around the genome
Capsid viruses
34
delivered to cell membrane by vesicular transport (Budding).
Enveloped virus
35
Virus can be released after lysis of the cell, by ________, or by ______ from the plasma membrane.
exocytosis, budding
36
buds into the ER and Golgi membrane.
Flavi-, Corona-, bunyavirus
37
assemble in nucleus and buds in and out of the adjacent ER
HSV
38
Properties of DNA viruses: Requires cell undergoing DNA synthesis to replicate
Parvovirus
39
Properties of DNA viruses: Stimulates cell growth and DNA synthesis
Papillomavirus and Polyomavirus
40
Properties of DNA viruses: Stimulates cell growth, cell makes RNA intermediate, encodes a reverse transcriptase
Hepadnavirus
41
Properties of DNA viruses: Stimulates cellular DNA synthesis and encodes its own polymerase
Adenovirus
42
Properties of DNA viruses: Stimulates cell growth, encodes its own polymerase and enzymes to provide deoxyribonucleotides for DNA synthesis, establishes latent infection in host
Herpesvirus
43
Properties of DNA viruses: Encodes its own polymerases and enzymes to provide deoxyribonucleotides for DNA synthesis, replication machinery, and transcription machinery in the cytoplasm
Poxvirus
44
(+) RNA genome resembles mRNA and is translated into a polyprotein, which is proteolyzed. A (-) RNA template is used for replication.
Picornaviruses, Togaviruses, Flaviviruses, Caliciviruses, and Coronaviruses
45
(-) RNA genome is a template for individual mRNAs, but full-length (+) RNA template is required for replication.
Orthomyxoviruses, Paramyxoviruses, Rhabdoviruses, Filoviruses, and Bunyaviruses
46
(+/-) Segmented RNA genome is a template for mRNA (+RNA). (+) RNA may also be encapsidated to generate the (+/-) RNA and then more mRNA.
Reoviruses
47
(+) RNA genome is converted into DNA, which is integrated into the host chromatin and transcribed as a cellular gene
Retroviruses
48
Cytopathogenesis Failed infection
abortive infection
49
Cytopathogenesis Cell death
lytic infection
50
Cytopathogenesis Replication without cell death
persistent infection
51
Cytopathogenesis Presence of virus without virus production but with potential for reactivation
latent-recurrent infection
52
Inclusion Bodies Negri bodies (intracytoplasmic)
Rabies
53
Inclusion Bodies Intranuclear basophilic (Owl's eye)
Cytomegalovirus (enlarged cells), adenoviruses
54
Inclusion Bodies Cowdry type A (intranuclear)
HSV, subacute sclerosing panencephalitis (measles) virus
55
Inclusion Bodies Intracytoplasmic acidophilic
Poxviruses
56
Inclusion Bodies Perinuclear cytoplasmic acidophilic
Reoviruses
57
Tissue culture: Primary
monkey kidney cells (influenza virus)
58
Tissue culture: Diploid cell line
fibroblastic cells (HSV, VZV, CMV)
59
Tissue culture: Tumor or immortalized cell line
HeLa cells (RSV, HSV)

Virology (5 decks)

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