Introduction Flashcards

exam 3

1
Q

clostridium dificile shape?

A

Rod-shaped

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2
Q

clostridium dificile is gram positive or negative?

A

positive

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3
Q

clostridium dificile is a strict _______

A

anaerobe

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4
Q

clostridium dificile synthesizes two large toxin proteins ____ and ____ that disrupt the _______________

A

clostridium dificile synthesizes two large toxin proteins TcdA and TcdB that disrupt the intestinal epithelium

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5
Q

clostridium dificile is _____- forming

A

spore

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6
Q

Prokaryotes vs Eukaryotes:

Nuclear membrane

A

Prokaryotes: No

Eukaryotes: Yes

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7
Q

Prokaryotes vs Eukaryotes:

Membrane-bound organelles

A

Prokaryotes: No

Eukaryotes: Yes

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8
Q

Prokaryotes vs Eukaryotes:

Endocytosis

A

Prokaryotes: No Eukaryotes: Yes

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9
Q

Prokaryotes vs Eukaryotes:

Volume

A

Prokaryotes: 1 um3
Eukaryotes: 1000 um3

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10
Q

Spore forming pathogens:

pseudomembranous colitis

A

clostridium difficile

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11
Q

Spore forming pathogens:

botulism

A

clostridium botulinum

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12
Q

Spore forming pathogens:

tetanus

A

clostridium tetani

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13
Q

Spore forming pathogens:

anthrax

A

Bacillus anthracis

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14
Q

Spore forming pathogens:

Food poisoning

A

Bacillus cereus

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15
Q

spastic paralysis

A

tetanus

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16
Q

flaccid paralysis

A

botulism

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17
Q

the _____ water count of spores allows them to survive harsh environmental conditions

18
Q

sporulation is triggered by

A

nutritional limitation

19
Q

terminal electron acceptor for respiration= oxygen

A

strict aerobes

20
Q

Terminal electron acceptor for respiration= organic molecule

A

Strict anaerobes

21
Q

some bacteria satisfy all of their energy needs by synthesizing ATP through the enzymatic reactions of glycolysis

A

fermentation

22
Q

bcteria generate additional ATP through an electron transport chain and membrane-bound ATP synthase

A

Respiration

23
Q

bacteria that have no requirements for organic compounds other than a simple carbon source

A

prototrophs

24
Q

bacteria that have more complex nutritional requirments, typically requiring amino acids and/or vitamins and/or pyrimidines and/or purines

A

Auxotrophs

25
C.Difficile is a natural
auxotroph
26
bacteria are
prokaryotes
27
Human pathogen, causative agent of antibiotic-associated diarrhea and pseudomembranous colitis
Clostridium difficile
28
Thick layer of peptidoglycan, has a bi-layer
Gram positive
29
thin peptidoglycan, contains endotoxin and lipopolysaccharide with one layer
Gram negative
30
what is one way that bacteria can fight anti-biotics?
their cell envelope
31
purple stain
gram positive
32
pink stain
gram negative
33
polysaccharide chains cross-linked by short chains of amino acids
peptidoglycan
34
D-ALA D-ALA
penicilllin
35
prevents the cross link being formed
Penicillin
36
pencillin only kills
growing cells
37
bacteria grow by
binary fission
38
Can bacteria grow fast?
Yes!!! and spread fast!
39
poor carbon source
poor medium
40
How does C. difficile, a strict anaerobe, | get transmitted from one person to another?
Spores
41
Why are there outbreaks of C. difficile infection in hospitals or long-term care facilities?
Spores and antibiotic use