Introduction lecture Flashcards

1
Q

What is a parasite?

A

organism that lives on or in a host organism and gets its food from or at the expense of its host

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2
Q

What is parasitism?

A
  • is a form of symbiosis, in which the parasite, usually the smaller
  • symbiont, is metabolically dependent on the host.
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3
Q

What is the relationship between host and parasite?

A
One symbiont (host) is harmed, while the other 
symbiont (parasite) benefits.
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4
Q

What are the characteristics of a parasite?

A
  • Depends on the host for survival
    • Has adverse effects on the host
    • Has greater fecundity than host
    • Is usually smaller than its host
    • Doesn’t want to kill its host
    host dies-parasite dies
    • In the case of Macroparasites
    (Helminths) – Are over-dispersed among the host population
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5
Q

How can a parasite harm a host?

A
  • Cause clinical/sub-clinical diseases
  • Trauma
  • Nutrient Robbing
  • Toxin production
  • Inflammatory responses/ Interaction with host immune
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6
Q

Why do we study parasites in veterinary medicine?

A
  • Impact animal health/welfare, Economic loss
  • Negatively impact the human-animal bond
  • Pose a challenge in wildlife conservation
  • Pose a risk to human health. Parasitic zoonoses
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7
Q

What is a direct life cycle?

A

Free living —> Host, no intermediate hosts

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8
Q

What is an indirect lifecycle?

A

Egg/Larvae in another host(s)–> host. Intermediate hosts present.

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9
Q

What is the lifecycle shown in this picture?

A

Direct lifecycle

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10
Q

What kind of lifecycle is shown in this picture?

A

Indirect

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11
Q

What is a microparasite?

A

E.g. Protozoa, Viruses (Malaria, Giardia, Toxoplasma)

  • Tiny, Unicellular, microscopic
  • Multiply within hosts
  • Short life cycles
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12
Q

What are macroparasites?

A

E.g. Roundworms, Tapeworms, Ticks, Fleas

Large, Multicellular, adult macroscopic

Reproduce in definative hosts

Generally longer life cycles

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13
Q

What are endoparasites?

A
  • Adults inside body of host
    eg: Nematodes, tapeworms, giardia
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14
Q

What are ectoparasites?

A

Parasites that live on the body of the host.

E.g. Ticks, mites, bugs, flies, mosquitos

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15
Q

What are facultative parasites?

A
  • Both parasitic and non parasitic lifestyles
  • opportunistic parasite, can complete lifecycle without hosts.
    eg: strongyloides spp
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16
Q

What is an Obligatory parasite?

A

Only parasitic stage- no free living environmental stage

eg: trichinells spp. Plasmodium spp.

17
Q

What are Spurious parasites?

A

Incidental finding. Parasite is found in unusual host. Usually resulted from predation or accidental ingestion/ contamination.

Eggs/ larvae do not develop in unusual host

18
Q

What is a pseudoparsite?

A
  • object or organism that resembles or is mistaken for a parasite.
19
Q

What are the three major groups of parasites?

A
  • Protozoa
  • Helminths
  • Arthropods
20
Q

How do protazoa reproduce and are they single celled or multicellular?

A

Single celled - microscopic • Reproduce mostly asexually -
Multiply and increase in number • Some sexually – fusion of
gametes
e.g. Giardia, Cryptosporidium Toxoplasma, E. coli

21
Q

What is some important information on Helminths?

A

Multicellular – Adults easily visible • Produce offspring • Well developed organs, systems • Prepatent period and patency is
long
e.g: Hookworm, Tapeworms, Flukes

22
Q

What is some important information about arthropods?

A
  • Multicellular – Visible
  • Segmented bodies, jointed limbs

• Parasites themselves or vectors
of other microbes

• Insects – 6 legs

• Arachnids 8 legs (adult)
e.g. Flies, ticks, mites

23
Q

What is definitive host?

A

Main host. Supports sexual reproduction of the parasite. Parasite reaches
sexual maturity. E.g. Dogs for Toxocara canis

24
Q

What is an intermediate host?

A

Supports the parasite’s development and asexual reproduction
(multiplication)—E.g. Slugs and snails for some lungworms.

25
What is a paratenic host?
Development, multiplication does not occur in this host. Help in maintaining the lifecycle but not necessary. E.g., Rodents for some nematodes
26
What is a transport host?
Carrier of the parasite from one host to another. No development or multiplication. E.g., Houseflies for some parasites. Aka mechanical hosts.
27
What is an aberrant/ unusual host?
Non-natural host. The parasite may cause pathology in aberrant hosts. E.g., Dogs are aberrant intermediate hosts for Racoon roundworms.
28
What is a vector?
- Carrier of an infectious agent between organisms of a different species. Can be intermediate hosts or transport hosts. Usually used in case of human infections. E.g., mosquitoes for heartworm, malaria.
29
What is a reservoir host?
Maintains the infection without being harmed—e.g., White-tailed deer for brainworm.
30
What are the routes of transmission?
* Fecal-oral- most intestinal parasites (Giardia, hookworms) * Skin penetration ( per-cutaneous)- bot fly * Vector transmission/ innoculation- heartworm via mosquitos * Direct contact : ectoparasites * Sexual transmission- Tritichomonas foetus * Vertical transmission: mother to offspring * Placental/ Prenatal (toxocara canis) * Through milk- Transmammary/ Lactogenic transmission (eg: ancyclostoma spp.) * Iatrogenic Transmission: Blood transfusion through contaminated surgical instruments, needles. (e.g. Blood protozoa, bacteria, virus)
31
How do you diagnose parasites?
* Fecal test * Float, Sedimentation, Qualatative, Quantitative * Urinalysis- ex dioctophyme * Examination of blood * Blood protazoans, arthropods, and some helminths * Direct smear, stained smear, knotts test (HW disease) * Exam of tissue * Ex: Trichinella * Tissue digestion/ tissue squash * Exam of hair/ skin * Primarily ectoparasites. Ex: fleas mites, lice * Skinscrape, KOH digestion of scrape, direct observation. * Necropsy * Fatal cases * Adult parasites/ stages, characteristic lesions formed by parasites. * Histopathology * PCR/Genetic Markers * Species level ID * Primers/ probes used to amplify species specific genetic markers * can be done from extracted egg/larvae/ adult. * Immunological Tests: Elisa, IFA, CFT, ect. * Serological tests- tests for antibodies against parasites * In house testing * Commercial tests.
32
What are the important methods of parasite management or control?
- Kill/Neutralize the parasites in the definitive hosts – Antiparasitic drugs - Prevent or reduce the production of offspring in the host - Immunization - Vaccines - Optimize host health to resist transmission - Kill/clear free-living stages in the environment - Prevent contact with/consumption of intermediate/paratenic hosts - Kill/neutralize intermediate/paratenic hosts BREAK THE LIFECYCLE
33
What is a serious emerging issue in parasitology?
Drug resistance - Judicial use of paraciticides is critical
34