Introduction to ATMP

Question 1

Gene Therapy

Answer 1

Introduces, removes or changes genetic material to treat diseases

Question 2

Cell Therapy

Answer 2

Uses live cells to replace damaged cells or modify immune responses

Question 3

Tissue-Engineered Products

Answer 3

Regenerates, repairs, or replaces damaged tissues

Question 4

Gene Therapy: In Vivo

Answer 4

Directly introduces therapeutic genes into the body

Question 5

Gene Therapy: Ex Vivo

Answer 5

Cells are removed, modified in a lab, and reintroduced into the patient

Question 6

CAR-T cell therapy

Answer 6

Chimeric Antigen Receptor T-Cell Therapy use to treat cancers

Question 7

Cell Therapy: Autologous Treatments

Answer 7

Uses the patient’s own cells, reducing rejection risks
Safer but time consuming due to the process of taking cells out from the patient, isolate and grow cultures from it and put it back

Question 8

Cell Therapy: Allogeneic Treatment

Answer 8

Uses cells from a compatible donor, more scalable but higher risk of immune rejection thus may require immune suppression

Question 9

Tissue-Engineered Products Applications

Answer 9

Orthopedics - Scaffold-based tissue repairs
Dermatology - Lab-grown skin grafts for burns or wounds
Transplantation - Potential for organ repair and replacement