Introduction to Cytogenetics and It's History Flashcards

(53 cards)

1
Q

study of heredity and variation

A

genetics

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2
Q

it is the difference in genetic sequence

A

variation

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3
Q

what is the study that refers to the transmission of traits and biological aspects from one generation to another?

A

heredity

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4
Q

three (3) primary sources of genetic variation

A

(1) mutations
(2) sex
(3) gene flow

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5
Q

areas of genetics

A

(1) classical genetics
(2) molecular genetics
(3) evolutionary genetics

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6
Q

classical genetics is based on:

A

mendel’s law of:

(1) law of dominance
(2) law of segregation

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7
Q

mendel’s law

A

(1) law of dominance
(2) law of segregation
(3) law of independent assortment

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8
Q

molecular genetics is based on:

A

central dogma of molecular genetics

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9
Q

evolutionary genetics is based on:

A

natural selection by charles darwin

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10
Q

matching type: areas of genetics

mendel’s principle

A

classical genetics

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11
Q

matching type: areas of genetics

structure of dna

A

molecular genetics

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12
Q

matching type: areas of genetics

quantitative genetics

A

evolutionary genetics

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13
Q

matching type: areas of genetics

meiosis and mitosis

A

classical genetics

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14
Q

matching type: areas of genetics

chemistry of dna

A

molecular genetics

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15
Q

matching type: areas of genetics

hardy-weinberg equilibrium

A

evolutionary genetics

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16
Q

matching type: areas of genetics

sex determination

A

classical genetics

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17
Q

matching type: areas of genetics

transcription

A

molecular genetics

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18
Q

matching type: areas of genetics

assumption of equilibrium

A

evolutionary genetics

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19
Q

matching type: areas of genetics

sex linkage

A

classical genetics

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20
Q

matching type: areas of genetics

translation

A

molecular genetics

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21
Q

matching type: areas of genetics

evolution

A

evolutionary genetics

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22
Q

matching type: areas of genetics

chromosomal mapping

A

classical genetics

23
Q

matching type: areas of genetics

dna cloning and genomics

A

molecular genetics

24
Q

matching type: areas of genetics

speciation

A

evolutionary genetics

25
# matching type: areas of genetics cytogenetics (chromosomal changes)
classical genetics
26
# matching type: areas of genetics control of gene expression
molecular genetics
27
# matching type: areas of genetics dna mutation and repair
molecular genetics
28
# matching type: areas of genetics extrachromosomal inheritance
molecular genetics
29
# mid 1800s discoveries the theory of evolution by natural selection
the origin of species
30
# mid 1800s discoveries published the origin of species, where theory requires heredity to work
charles darwin (1859)
31
# mid 1800s discoveries published experiments in plant hybridzations, which lays out the basic theory of genetics
gregor mendel (1866)
32
# mid 1800s discoveries isolated nucleic acid from pus cells
friedrich miescher (1869)
33
# mid 1800s discoveries proved that the genetic material is needed located in the nucleus
ernst haeckel (1871)
34
# major events in the 20th century rediscovery of mendel's work
carl correns, hugo de vries, and erich von tschermak (1900)
35
# major events in the 20th century discovered that alkaptonuria is a genetic human disease
archibald garrod (1902)
36
# major events in the 20th century coined "gene"
wilhelm johannsen (1902)
37
# major events in the 20th century - discovered linkage between genes - coined "genetics"
william bateson (1904)
38
# major events in the 20th century - discovered the science of genetic linkage - coined "epistasis"
reginald punnett & william bateson (1910)
39
# more 20th century events - proved that genes are located in chromosomes through fruit flies (drosophilia) - first discovered chromosomal differences between a male and a female
thomas hunt morgan (1910)
40
# more 20th century events - began the study of quantitative genetics by partioning phenotypic variance into a genetic and an environmental component
ra fisher (1918)
41
# more 20th century events showed x-ray mutations through fruit flies
hermann j. muller (1926)
42
# more 20th century events - showed that dna can transform bacteria, demonstrating dna is the hereditary material
oswald avery, colin macleod, and maclyn mccarty (1944)
43
# more 20th century events determine the structure of dna molecule, which leads directly to knowledge of how it replicates
james watson and francis crick (1953)
44
# more 20th century events solves the genetic code, showing the 3 dna base codes for one amino acid
marshall nirenberg (1966)
45
# more 20th century events dna base codes for one amino acid
a - adenine c - cytosine g - guanine u - uracil
46
# more 20th century events - an enzyme found in retroviruses used in cloning genes - makes dna and rna template
reverse transcriptase (1970)
47
# more 20th century events first to create a recombinant dna molecule
paul berg (1972)
48
# more 20th century events combined the dna from two different species in vitro then transforming it into bacterial cell (first cloning)
stanley cohen and herbery boyer (1972)
49
# more 20th century events introduced the process of sequencing the genome of a bacteriophage
frederick sanger (1977)
50
# more 20th century events invented the polymerase chain reaction (pcr)
kary mullis (1983)
51
# more 20th century events to sequence and map the genome of man
the human genome project (1990)
52
# more 20th century events successfully cloned dolly the sheep
ian wilmut and keith campbell (1996)
53
# more 20th century events sequence of the entire human genome
2003