Flashcards in Introduction to Immunology (Module 1) Deck (17)
_______________ is the study of how the body responds to protect itself from foreign agents as bacteria, viruses, fungi, parasites, chemical irritants, toxins and malignant (cancer) cells.
____________ is the ability to respond to foreign antigens (the ability to resist disease).
What are the two main categories of immunity?
Innate immunity or Natural Immunity
Adaptive Immunity or Acquired Immunity
_______ _______ ________ us the coordinated action of the immune system to foreign agents.
The Immune Response
What does Innate (natural) immunity describe?
All of the defense mechanisms that are present from birth and protect an individual from injury by foreign or abnormal agents
What are the 6 innate immunity defense mechanisms?
Chemicals and Anti-microbials
Phagocytes (neutrophils and monocytes) and Natural Killer Cells
Acute Phase Reactants
________ ________ ________ are produced by the liver in increased amounts as part of the innate immune response to infection/inflammation.
Acute phase proteins
Alpha 1 - Antitrypsin
Alpha 2 - Macroglobulin
100-1000X; 6 hours post injury
2-4X; 24-48 hours post injury
____________ ___________ is mediated by lymphocytes and is _________ or _________ as we encounter challenging agents.
learned or acquired
What are the 5 adpative mechanisms for the immune system?
Adaptive immunity is centered on two main components, _________ immunity and _________ cellular immunity,
____________ ______________ involves the production of soluble plasma proteins called immunoglobulins.
The humoral immune system deals with __________ ___________.
___________ __________, as the name implies, involves cells, such as T-lymphocytes.
The secondary lymphoid tissue consists of the _______ __________, ___________, and ____-___________ _______ __________
lymph nodes, spleen, and mucosa associated tissue.
What do the secondary lymphoid structures servce two functions.
1- Trap and concentrate foriegn antigens
2- Serve as the site where T and B cells encounter specific foreign antigen and differentiate and proliferate to form many antigens specific lymphocytes.