Introduction to Immunology (Module 1) Flashcards Preview

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Flashcards in Introduction to Immunology (Module 1) Deck (17)
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1

_______________ is the study of how the body responds to protect itself from foreign agents as bacteria, viruses, fungi, parasites, chemical irritants, toxins and malignant (cancer) cells.

Immunology

2

____________ is the ability to respond to foreign antigens (the ability to resist disease).

Immunity

3

What are the two main categories of immunity?

Innate immunity or Natural Immunity
Adaptive Immunity or Acquired Immunity

4

_______ _______ ________ us the coordinated action of the immune system to foreign agents.

The Immune Response

5

What does Innate (natural) immunity describe?

All of the defense mechanisms that are present from birth and protect an individual from injury by foreign or abnormal agents

6

What are the 6 innate immunity defense mechanisms?

Mechanical Barriers

Chemicals and Anti-microbials

Phagocytes (neutrophils and monocytes) and Natural Killer Cells

Inflammation

Complement

Acute Phase Reactants

7

________ ________ ________ are produced by the liver in increased amounts as part of the innate immune response to infection/inflammation.

Acute phase proteins

8

C-reactive protein
Haptoglobin
Fibrinogen
Alpha 1 - Antitrypsin
Ceruloplasmin
Alpha 2 - Macroglobulin

100-1000X; 6 hours post injury
2-4X
2-4X; 24-48 hours post injury
2-4X
50 percent
50 percent

9

____________ ___________ is mediated by lymphocytes and is _________ or _________ as we encounter challenging agents.

Adaptive immunity
learned or acquired

10

What are the 5 adpative mechanisms for the immune system?

Self Discrimination

Specificity/diversity

Adaptiveness/Specialization

Memory

Deactivation Mechanisms

11

Adaptive immunity is centered on two main components, _________ immunity and _________ cellular immunity,

humoral
cellular

12

____________ ______________ involves the production of soluble plasma proteins called immunoglobulins.

Humoral immunity

13

The humoral immune system deals with __________ ___________.

extracellular antigens.

14

___________ __________, as the name implies, involves cells, such as T-lymphocytes.

Cellular immunity

15

The secondary lymphoid tissue consists of the _______ __________, ___________, and ____-___________ _______ __________

lymph nodes, spleen, and mucosa associated tissue.

16

What do the secondary lymphoid structures servce two functions.

1- Trap and concentrate foriegn antigens
2- Serve as the site where T and B cells encounter specific foreign antigen and differentiate and proliferate to form many antigens specific lymphocytes.

17

The _________ is responsive to blood borne antigens.

The ______ ___________ protect the body from antigens that gain entry from the skin/tissues.

The __________ protects the mucosal surfaces of the body

Spleen

Lymph Nodes

Malt