Introduction to Lab Medicine Flashcards
(33 cards)
A field of science devoted to the production, care, and study of lab animals used in biomedical research and education
Lab Animal Science
The first person to experiment on living animals
Aristotle
Developed the germ theory by introducing anthrax to sheep
Louis Pasteur
The theory that microorganisms cause disease
Germ Theory
90-95% of research animals
Mice and rats
Used dogs to describe classical conditioning
Ivan Pavlov
Developed the polio vaccine using rhesus macaques
Jonas Salk
The first mammal successfully cloned from adult cells
Dolly the sheep
The primary species of fish used in research
Zebra fish
Used for flu research
ferrets
Large company that breeds animals for research
Charles River
Company that produces rodents for research
JAX
Company that produces NHPs for research (Non-human primates)
Alphagenesis
Goats and sheep are primarily used in research for
cardio research
Used with emetic research
shrews
Found in horseshoe crab blood as opposed to HgB
hemocyanin
The American Veterinarian Medical Association
AVMA
American Association for Lab Science
Certifies at 3 levels
AALAS
A book published by the Institute of Lab Animal Resources
The Guide for the Care and Use of Lab Animals
Institutional Animal Care and Use Committee
Consists of a vet, an outside member, a practicing scientist, and a member with no scientific background
Announced inspections 2x a year
Reviews and okays protocols
IACUC
How long are protocols good for?
3 years
Written document that explains the use of animals, how many, and why they are needed
protocols
United States Department of Agriculture
Does unannounced inspections of facilities once a year
Looks at record keeping, ID of animals, and procedures completed
USDA
Associations for Assessment and Accreditation of Lab Animals Care
Private, nonprofit organization
Promotes humane treatment of animals in science through VOLUNTARY accreditation and assessment programs
Commited to responsible animal care and use
Inspections every 3 years
AAALAC