Introduction to metabolism Flashcards

(37 cards)

1
Q

True or False: Nathan loves Biochemistry very much

A

Yes!!! <3

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2
Q

Where ETC happens..

A

inner mito membrane

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3
Q

The final common pathway by which electrons

derived from different fuels of the body flow to oxygen

A

ETC

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4
Q

The inner mitochondrial
membrane is impermeable to most
small ions, including and small molecules such as j
ATP, ADP, pyruvate, and other metabolites important to mitochon­drial function. True or False

A

True!

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5
Q

Convlutions of the Inner Mitochondrial Membrane

A

Cristae

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6
Q

Capacity to do work

A

Energy

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7
Q

Energy in the process of doing work

A

Kinetic

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8
Q

Energy content due to arrangement or position of matter

A

Potential

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9
Q

study of energy transformations that

occur in a collection of matter

A

Thermodynamics

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10
Q

the study of energy in living systems;

Thermodynamics applied to living organisms

A

Bioenergetics

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11
Q

The amount of energy in the universe in CONSTANT but

not homogenous. T or F

A

True

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12
Q

Energy cannot be created nor destroyed, but only

converted to other forms.

A

First law of thermodynamics

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13
Q

Every reaction results in an increase in entropy and the loss of usable energy (free energy) as heat. T or F

A

True

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14
Q

EQUATIONS OF ENERGY

A
∆G = G B  – G A  
∆H = H B  – H A
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15
Q

Free energy difference of a system in STANDARD

CONDITION (i.e. 25ºC, 1 atm)

A

∆G^0

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16
Q

Catabolic Pathways endergonic or exergonic?

A

Exergonic Rxns=Those that release energy by breaking down complex molecules into simpler compounds such as glycolysis

17
Q

It measures the tendency of oxidant to gain electrons and

to become reduced; This is potential energy

A

Reduction potential

18
Q

More positive= Higher reduction potential. torf

19
Q

The more POSITIVE the reduction potential difference is,

the easier the redox reaction. TorF

20
Q

Oxidation of foods can be used to synthesize ATP. TorF

21
Q

loss of hydrogen

A

Dehydrogenase

22
Q

gain of oxygen

23
Q

electron transfer to molecular oxygen

24
Q

Electrons move from a carrier with ___ redox potential to a carrier with ___ redox potential

A

lower; higher

25
``` Anabolic reactions ____ energy to synthesize complicated molecules from simpler compounds a reductive process that requires energy ```
consume
26
``` Catabolic reactions ___ energy by breaking down complex molecules into simpler compounds an oxidative process that releases energy ```
release
27
Contents of atp
ribose, adenine, phosphate
28
makes inner membrane impermeable to ions
cardiolipin, which has 4 FA
29
A multi-enzyme complex which catalyzes the conversion of | pyruvate (produced from glycolysis) to acetyl-CoA
Pyruvate dehydrogenase complex
30
Mnemonics for Krebs Cycle
Can I keep selling sex for money, oficer?
31
Proposes that energy from ETC is stored in a high-energy | phosphate intermediate and drives ATP synthesis
Chemical Coupling Hypothesis
32
Proposes that energy from ETC is stored in a high-energy | protein conformation
. Conformational Coupling Hypothesis
33
Requires an intact membrane & ADP supply to open F 0 – F 1 channel The electron gradient created in sensed by the F 0 – F 1 ATP synthase, which pumps H + into the matrix; it undergoes conformational change, allowing H + to enter
Chemiosmotic Hypothesis
34
Dissolve in the membrane and function as carriers for H + - does not involve direct binding to any protein in ETC or ATP synthase
Uncoupling Reagents (Uncouplers) (ex dinitrophenol)
35
High [ATP] or low [ADP] & [AMP] ____ rate of glycolysis, | pyruvate oxidation, acetate oxidation via CAC & OP
Lowers
36
The interlinking of glycolysis & CAC by citrate (which inhibits glycolysis) supplements the ______ system
adenine nucleotide
37
↑levels of NADH & acetyl-CoA also _____ oxidation of pyruvate to acetyl CoA, and a high [NADH]/[NAD + ] ration ____ dehydrogenase reactions of CAC
both inhibit