Investigations of MS Flashcards

(31 cards)

1
Q

funcion of x ray

A

to detect skull fractures after head trauma

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2
Q

positioning for X Ray

A

AP
PA
Lateral

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3
Q

Function of computerised tomography

A

detect acute haemorrhage
assess depressed and comminuted skull fractures
can visual bleeding e.g. extradural haematomas, subdural haematomas, actively bleeding parenchymal haemorrhages, brain herniation

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4
Q

describe density in computerised tomography

A

white = most dense
black = least dense

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5
Q

process of cerebral angiography

A

catheter inserted in femoral artery and manouvered to carotid or vertebral origin
contrast injected with high pressure pump

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6
Q

benefits of cerebral angiography

A
  • Disorders of the cerebrovascular circulation
  • Aneurysm
  • Arterio-venous malformation
  • Transient ischaemic attack
  • Cranial arteritis
  • Vascular tumour (haemangioblastoma, angioma)
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7
Q

describe process of MRI

A

Magnetic field forces H+ protons in body to orient to that field.
radiofrequency is pulsed through patient protons spin out of equilibrium
current switched off and MRI detects energy released when protons re-align w/ magnetic field
MRI - map of proton energy within tissue

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8
Q

benefits of using T1 weighted MRI

A

Better contrast between gray and white matter

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9
Q

benefits of using T2 weighted MRI

A

scans better for oedema

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10
Q

what colour is; water, fat, bone, inflammation, muscle, spinal cord, cortex, white matter in T1 weighted MRI

A

water - dark
fat - bright
bone - dark
inflammation - dark
muscle - grey
spinal cord - grey
cortex - grey
white matter - bright (myelin or fat sheath in axons)

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11
Q

what colour is; water, fat, bone, inflammation, muscle, spinal cord, cortex, white matter in T1 weighted MRI

A

water - bright
fat - bright
bone - dark
inflammation - bright
muscle - dark grey
spinal cord - light grey
cortex - light grey
white matter - dark grey (myelin or fat sheath in axons)

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12
Q

absolute contraindications for MRI

A

Ferrous metallic foreign bodies - old gunshot shrapnel, older types of fracture fixation
implanted electrical medical devices - cochlear, pacemaker, insulin pump
pregnancy
claustrophobic

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13
Q

purpose of lumbar puncture

A

obtain CSF

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14
Q

Positioning for lumbar puncture

A

side lying knees to chest
needle in L4-L5

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15
Q

Precautions for lumbar puncture

A
  • Raised CSF
  • Tentorial herniation-coning
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16
Q

what is an elevated white cell count in CSF indicative of

A

metastatic tumour

17
Q

what is an elevated erythrocyte cell count in CSF indicative of

18
Q

what is an protein in CSF indicative of

A

polyradiculitis or guillain barre syndrome

19
Q

what is the presence of oligoclonal bands in CSF indicative of

A

IgG synthesis - MS

20
Q

Contraindications of lumbar puncture

A
  • Raised intra-cranial pressure (ICP)
  • Coagulation disorder
  • Vertebral deformity
21
Q

process of positron emission tomography

A

radiation introduced in body using radiotracer
radiation accumulates in organs and measured when it emits small energy - gamma rays which ill be detected
indicate body function e.g blood flow, oxygen uptake

22
Q

complications of lumbar puncture

A

Headache (10%)
Radicular pain (10%)
Tonsillar herniation (extremely rare)

23
Q

function of muscle biopsy

A

Essential in diagnosis of
inflammatory myopathies
metabolic myopathies

24
Q

process of electro-encephalography

A

Recording of cerebral electrical potentials by electrodes on the scalp
* Abnormalities reflect general pathological processes NOT specific diagnoses

25
Electro-encephalography detects what pathological conditions
* Epilepsy * States of altered consciousness Post traumatic and anoxic coma * Parasomnias * Dementias * Toxic confusional states * Cerebral infections * Encephalopathies
26
describe electromyography process
Recording of electrical activity within a muscle Diagnostic EMG involves insertion of needles into muscle to record and observe motor unit action potentials
27
nerve conduction studies
* Peripheral nerve (motor or sensory) stimulated * Time from stimulus  response (muscle contraction) is calculated * Conduction velocity = distance between two sites divided time taken
28
factors affecting nerve conduction studies
* Age * Body Temperature * Pathology Delay occurs with Nerve entrapments Demyelinating polyneuropathy Multifocal motor neuropathy * Repeated stimulation: Myasthenia Gravis
29
describe evoked potentials
Measure the electrical activity of the brain in response to stimulation of specific sensory nerve pathways
30
types of evoked potentials
visual - diagnose ms Somatosensory - monitoring during surgery Motor - via transcranial magnetic stimulation of head
31
electronystagmography
Electrical measurement of nystagmus (abnormal beating of the eyes)