Ipratropium Bromide (Atrovent)

Question 1

What are its classifications?

Answer 1

-Anticholinergic
-Parasympatholytic

Question 2

What are its mechanisms of action?

Answer 2

-Causes bronchodilation by competitive inhibition of cholinergic receptors on bronchial smooth muscle
-Blocks the action of acetylcholine, which inhibits parasympathetic stimulation, decreasing bronchial secretions
-Dries respiratory tract secretions

Question 3

What are its indications for use?

Answer 3

-Bronchial Asthma
-Bronchospasm associated with COPD.

Question 4

What contraindications does it have?

Answer 4

-Known hypersensitivity
-Is not indicated for acute treatment of bronchospasm for which rapid response is required
-Ischemic chest pain
-Acute narrow-angle glaucoma.

Question 5

What are the dosages? hint 1/2 to get ped dose

Answer 5

A: -250-500mcg mixed with
ventolin q 20 minutes, 2
doses
-2-4 puffs q 20 minutes x 3
doses

P: -125-250mcg mixed with
ventolin and/or NS to a
minimum of 2cc
-1-2 puffs

Question 6

What side effects does it have?

Answer 6

-Palpitations
-Anxiety
-Dizziness
-Headache
-Nervousness
-Rash
-Nausea/Vomiting

Question 7

What are the precautions for this medication?

Answer 7

-Narrow Angle Glaucoma
-Pts with BPH (Benign prostatic hyperplasia) and/or Bladder-Neck obstruction.