Iron deficiency and iron-deficiency anaemia in women’s health 2017 TOG– Flashcards
(20 cards)
What is the most common micronutrient deficiency worldwide?
Iron deficiency
What proportion of women are iron deficiency in their reproductive years
20%
Non pregnancy definition of anaemia
↓120 g/l
What is Hepcidin?
25-amino acid peptide hormone that regulates iron uptake and release from stores in response to circulating and tissue levels of iron.
Ferric iron (Fe2+) and ferrous iron (Fe3+), which iron is better absorbed from the guy
Ferric iron FE2+
For every ml of blood lost, how much iron is lost?
0.5mg
A daily loss >5mg, exceeds body compensatory mechanism to increase iron absorption, reducing iron supple.
Causes of iron deficiency diagram
What proportion of of women with HMB bleeding are iron deficient
63%
Worldwide HMB account for what probation of iron deficiency?
20-30%
Causes of HMB
PALM-COEIN
Haemoglobin levels in non-pregnancy, pregnant, men
Investigations for iron deficiency and iron deficiency anaemia
- Hb
- Serum ferritin
- Transferrin Conc
- Soluble transferrin receptor
Ferritin < 15 - iron deficiency
For iron deficiency how much elemental iron should be taken?
100-200mg
Iron consent of oral iron preparations
- Ferrous fumate/sulphate
To maximise absorbtion of iron when should it be taken
At night or 1 hour before food
Do not take with tannins and milk
Ascorbic acid in fruit juice increase uptake
After commencing oral iron when should FBC and ferritin level be repeated
3-4 weeks (2 weeks in pregnancy)
How much should Hb raised in 3-4 weeks
20g/l every 3-4 week
1.2g/l days
Continue for 3 months
How quickly does parental iron increase iron levels
20g/l in 7 days
When in pregnancy should parental iron be avoided>
1st trimester
How much does 1 unit of RBC increase Hb
10g/l
