ISBB BLOOD COMPONENTS

Question 1

Provide blood volume expansion and RBC mass in acute blood loss

Answer 1

Whole blood

Question 2

Storage WB

Answer 2

1-6°C
Transport
1-10°C

Question 3

Increase rbc mass of symptomatic, normovolemic
patients

Answer 3

Packed
RBCs

Question 4

Packed RBCs storage

Answer 4

1-6C

Question 5

Increase RBC mass in patients with severe and/or recurrent febrile
transfusion reactions due to leukocyte antibodies. Increase
RBC mass in patients at risk for HLA Alloimmunization to HLA antigens or Susceptible to
CMV

Answer 5

Leukocyte
Reduced
RBCs

Question 6

Leukocyte Reduced RBCs storage

Answer 6

1-6c

Question 7

Leukocyte Reduced RBCs shelf life

Answer 7

Open system -
24 hours
Closed system
- same was
WB

Question 8

Increase RBC mass of symptomatic anemic patients with
history of allergic, febrile, urticarial, and anaphylactic
rxns.

Answer 8

Washed rbc

Question 9

Washed RBC shelf life

Answer 9

24 (hrs

Question 10

Storage rare blood and autologous
units

Answer 10

Frozen Rbc

Question 11

Frozen RBC can be stored at

Answer 11

-65c

Question 12

Frozen RBC shelf life

Answer 12

10 yrs.

Question 13

For bleeding due to
thrombocytopenia

Answer 13

Platelet concentrates
(RDP) - contains 5.5X10^10 per unit

Question 14

Platelet concentrates
(RDP) - contains 5.5X10^10 per unit STORAGE

Answer 14

20-24 continuous agitation

Question 15

Platelet concentrates
(RDP) - contains 5.5X10^10 per unit SHELF LIFE

Answer 15

5 days

Question 16

Correct multiple coagulation factor deficiency

Answer 16

Fresh frozen plasma
(FFP)

Question 17

Fresh frozen plasma STORAGE
(FFP)

Answer 17

-18 or colder

Question 18

Fresh frozen plasma
(FFP) SHELF LIFE

Answer 18

1 yr.

Question 19

True or false

FFP is prepared 6-8 hrs after collection
37°C thawing and transfused within 24 hours

Answer 19

True

Question 20

For treatment of fibrinogen deficiency, Hemophilia A, Von
Willebrand’s disease, andFactor XIII deficiency

Answer 20

Cryoprecipitate

Question 21

Cryoprecipitate is administered ___after thawing

Answer 21

6 hrs

Question 22

Cryoprecipitate is administered_ after pooling

Answer 22

4hr

Question 23

Cryoprecipitate storage

Answer 23

-18 or colder

Question 24

Cryoprecipitate shelf life

Answer 24

1yr

Question 25

plasma from which the cryoprecipitate concentrate has been harvested.

Answer 25

(Cryo-poor plasma or CPP) cryo reduced plasma

Question 26

CPP contains the residual albumin;

Answer 26

factors II, V, VII, IX, X, XI; and ADAMTS13

Question 27

Patients with Granulocyte Dysfunction or Myeloid Hypoplasia who are unresponsive to antibiotics

Answer 27

Granulocyte pheresis -contains 1x10^10 granulocytes /unit

Question 28

Granulocyte pheresis storage

Answer 28

20-24 without agitation

Question 29

Prevent or control bleeding in Hemophilia A patients

Answer 29

Factor VIII concentrate

Question 30

Factor VIII concentrate storage

Answer 30

1-6C lyophilized

Question 31

Factor VIII concentrate sources

Answer 31

Human source Porcine Factor VIII Recombinant Factor VIII

Question 32

Prevent or control bleeding in Hemophilia B patients

Answer 32

FACTOR IX CONCENTRATES

Question 33

Factor IX Concentrate storage

Answer 33

1--6 lyophilized

Question 34

FACTOR IX concentrates is available in three forms:

Answer 34

1. Prothrombin complex concentrates 2. Factor IX concentrates 3.Recombinant factor IX

Question 35

Replace loss of colloids in Hypovolemic shock, severe burns, or for pressure support during hypovolemic episodes

Answer 35

Albumin

Question 36

Albumin storage

Answer 36

1-6C lyophilized

Question 37

Factor VIII concentrate, Factor IX and albumin storage

Answer 37

Variable

Question 38

Prestorage leukoreduction- leukoreduction performed shortly after collection, usually within

Answer 38

72 hours

Question 39

Leukoreduced RBCs and whole blood are prepared using special filters (_____) that trap leukocytes and platelets but allow RBCs to flow through

Answer 39

multiple layers of polyester or cellulose acetate nonwoven fibers

Question 40

Two major filter types available in prestorage leukoreduction: • Whole blood is passed through the leukoreduction filter before centrifugation. *FILTER then CENTRIFUGE

Answer 40

Take note

Question 41

Cryoprotective agents can be categorized as:

Answer 41

Penetrating Nonpenetrating

Question 42

-Involves small molecules that cross the cell membrane into the cytoplasm

Answer 42

Penetrating cryoprotective agent

Question 43

Osmotic force of the agent prevents water from migrating outward as extracellular ice is formed, preventing intracellular dehydration. -E.g., glycerol

Answer 43

Penetrating cryoprotective agent

Question 44

Glycerol slow freezing HIGH GLYCEROL

Answer 44

40%

Question 45

High glycerol 20% slow freezing is frozen at _ and stored at _

Answer 45

-80 c -65 c

Question 47

High glycerol 20% slow freezing equipment used

Answer 47

Mechanical freezer

Question 48

Glycerol FAST FREEZING

Answer 48

20%

Question 49

20% Glycerol fast freezing

Answer 49

Low glycerol method

Question 50

20% Glycerol fast freezing low glycerol method is frozen and stored at room temperature? Using what equipment

Answer 50

-196 c -120 c Liquid nitrogen

Question 51

Glycerol in Agglomeration

Answer 51

79.2%

Question 52

79.2 Glycerol in AGGLOMERATION is frozen and stored at? Using what equipment?

Answer 52

Frozen-80 Stored-65 Mechanical freezer