ITE CA2 IV Anesthetics

Question 1

where propofol metab

Answer 1

liver and lung

Question 2

a drug that is eliminated in proportion to the concentration of the drug half life

Answer 2

first order kinetics

Question 3

etomidate effect on CSF production

Answer 3

decreased

Question 4

diazepam can cause what in utero

Answer 4

cleft palate

Question 5

name 4 drugs that cause pain on injection

Answer 5

diazepam, methohexital, propofol, etomidate

Question 6

therapeutic index

Answer 6

lethal dose/effective dose

Question 7

a drug cleared at a constant rate and not dependent on plasma concentration

Answer 7

zero order kinetics

Question 8

drug contraindicated in acute intermittent porphyria

Answer 8

barbiturates

Question 9

treatment options for intra-arterial barbiturate injection

Answer 9

intra-arterial lidocaine, intra-arterial papaverine, stellate ganglion block

Question 10

can cause convulsion-like EEG potentials in epileptic patients

Answer 10

etomidate

Question 11

MoA barbiturates

Answer 11

gaba-a receptor agonist

Question 12

propofol and placenta

Answer 12

can cross and cause resp depression

Question 13

name 4 drugs ass’d with histamine release

Answer 13

atracurium, morphine, meperidine, succ

Question 14

ketamine has active metabolite?

Answer 14

yes

Question 15

intrapulmonary (R to L) shunt effect on induction with IV agent

Answer 15

minimal/ no effect

Question 16

intracardiac (R to L) shunt effect on induction with IV agent

Answer 16

increased induction speed

Question 17

intracardiac (L to R) shunt effect on induction with IV agent

Answer 17

minimal/no effect