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IV anesthetics Flashcards

(49 cards)

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1
Q

Barbiturates:

name 3 short acting barbs

A

thiopental (penthothal)
Mexohexital (brevital)
Thiamylal (surital)

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2
Q

Barbiturates:
they have many CNS actions but, depression on the _____ undoubtablly contributes to the sedative and hypnotic actions of IV agents

A

Reticular Activating System (RAS)

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3
Q

Barbiturates:Thiopental

has what 2 actions

A

anticonvulsant

Amnestic

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4
Q

Barbiturates:Thiopental

what can occur in small doses

A

poor analgesic- may increase the reaction to painful stimuli, may be hyperalgesic

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5
Q

Barbiturates:Thiopental

does what to respiratory system

A

depresses it

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6
Q

Barbiturates:Thiopental

does what to myocardial contractility

A

depresses it.- decreases SV, CO, Arterial BP

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7
Q

Barbiturates:Thiopental

does what to HR

A

Increases it

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8
Q

Barbiturates:Thiopental

does what to cerebral vascular resistance? what does that mean?

A

increases CVR

hence decreases cerebral blood flow and ICP

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9
Q

Barbiturates:Thiopental

contraintidated in what pts?

A

porphoria (a neuro dz caused by inadequate porphyrin metabolism)

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10
Q

Barbiturates:Thiopental

what would u not use with asthmatics

A

histamine release

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11
Q

Barbiturates: methohexital has excitatory effects. what are they

A

hiccups

myoclonus

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12
Q

Propofol:

what is the 1/2 time to elimination

A

0.5-1.5 hrs

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13
Q

Propofol:

which causes a bigger drop in BP prop or thiopental

A

prop

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14
Q

Propofol:

which has bigger respiratory depression prop or thiopental

A

prop

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15
Q

Propofol:

has antiemetic effects b/c it works where

A

Chemorecptor trigger zone (CRTZ)

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16
Q

Propofol:

does it have antipruritic effects?

A

yes

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17
Q

Propofol:

does it produce analgesia

A

no

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18
Q

Propofol:

does it have anticonvulsant effects

A

yes

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19
Q

Propofol:

does what to CBF and CMRo2

A

decreases it

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20
Q

benzodiazepines:

enhance the action of what receptors

21
Q

benzodiazepines:

GABA are what?

Study These Flashcards
A

the brains major inhibitory transmitter

22
Q

benzodiazepines:

name 3 short acting benzos

Study These Flashcards
A

Diazepam (valium)
Lorazepam (ativan)
Midazolam (versed)

23
Q

benzodiazepines:

do they produce analgesia?

24
Q

benzodiazepines:

name 5 CNS effects

Study These Flashcards
A 
Antianxiety
Amnestic
Sedative
Hypnotic
anticonvulsant
25
benzodiazepines: | what CV effects
none unless pt is volume depleted then maybe hypotension
26
benzodiazepines: | does what to brain
cerebral vasoconstriction- lowers CBF and ICP
27
Ketamine: | produces anmesia and profound analgesia by interacting with what receptor
NMDA
28
Ketamine: | Does what to cerebral vasculature
Dilates it | so CBF increases and ICP increases
29
Ketamine: | does what to cerebral metabolism
increases it
30
Ketamine: | does what to eyes and tone
hypertonus and nystagmus
31
Ketamine: | what does it do to CV
Stimulates the SNS which promotes CV enhancement- increased HR, CO, and BP
32
Ketamine: | what pts are good canidates
trauma | elderly
33
Ketamine: | avoid in what pts
CAD Glaucoma Increased ICP
34
Ketamine: | emergence can be horrible explain to bad side effects
bad dreams Hallucinations n/v
35
Opioids: | why is morphine rarely used for anesthesia
histamine release
36
Opioids: | do what to respiratory system
depress it
37
Opioids: | are they cardiac stable
yep
38
Opioids: | can they produce treacle rigidity
yep
39
Opioids: | what do they do to cerebral blood flow
cerebral vasoconstricor | decreased CBF and ICP
40
Opioids: | why do they cause nausea
stimulate CRTZ
41
Opioids: | how do synthetic opioids cause bradycardia
stimulate the vagal nerve
42
Opioids: | if it caused sphincter of do spasm what can be given to relax it
glucagon 1-2mg
43
Etomidate: | cv effects
minimal
44
Etomidate: | how our it's analgesic and amnestic properties
poor
45
Etomidate: | does what to CBF and ICP
decreases it
46
Etomidate: | what should you look for on injection
pain
47
Etomidate: | what can it cause and how in pts with catecholamine depletion
adrenal cortical suppression | directly depresses cortisol output from the adrenal cortex
48
Etomidate: | does what to the immune system
depresses it
49
the CNS effects after bolus of an IV anesthestic are terminated primarily how
redistribution

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